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  • 38 Hits
  • Search Condition : Filter (MeSH = GTPase-Activating Proteins / metabolism*)
Species Resource Title
Yeast Stress-dependent inhibition of polarized cell growth through unbalancing the GEF/GAP regulation of Cdc42.
Human and Animal Cells TALL-1(RCB2084) Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia.
C.elegans tm2056 RhoGAP RGA-8 supports morphogenesis in C. elegans by polarizing epithelia.
Human and Animal Cells 293(RCB1637) Src Family Tyrosine Kinase Signaling Regulates FilGAP through Association with RBM10.
DNA material mCherry-hCdt1(30/120)/ pCSII-EF (RDB15273) , AmCyan-hGem(1/110)/pCSII-EF (RDB15274) APC(CDH1) targets MgcRacGAP for destruction in the late M phase.
Human and Animal Cells ATDC5(RCB0565) Spermidine activates RIP1 deubiquitination to inhibit TNF-α-induced NF-κB/p65 signaling pathway in osteoarthritis.
Human and Animal Cells COS-7(RCB0539) Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
C.elegans tm2790 , tm2907 Epidermal control of axonal attachment via β-spectrin and the GTPase-activating protein TBC-10 prevents axonal degeneration.
DNA material pMRX-bsr-ss-EGFP-FM4 (RDB17364) , pMRX-bsr-ss-EGFP-FM4-TMD (RDB17365) Differing susceptibility to autophagic degradation of two LC3-binding proteins: SQSTM1/p62 and TBC1D25/OATL1.
C.elegans tm2058 , tm2790 , tm2640 , tm3628 , tm3630 , tm2564 , tm1865 , tm2907 The small GTPase RAB-35 defines a third pathway that is required for the recognition and degradation of apoptotic cells.
Human and Animal Cells U251(RCB0461) Functional analysis of the DEPDC1 oncoantigen in malignant glioma and brain tumor initiating cells.
Human and Animal Cells HSC-2(RCB1945) , HSC-3(RCB1975) , HSC-4(RCB1902) , Sa3(RCB0980) , Ca9-22(RCB1976) , SAS(RCB1974) , HO-1-u-1(RCB2102) SIPA1 promotes invasion and migration in human oral squamous cell carcinoma by ITGB1 and MMP7.
C.elegans tm2241 The VPS34 PI3K negatively regulates RAB-5 during endosome maturation.
DNA material pmStr-N1-mouse Arf6 (RDB15387) , pEGFP-C1-mouse centaurin-b2-N610A/N691A (RDB15384). Rab35 regulates Arf6 activity through centaurin-β2 (ACAP2) during neurite outgrowth.
DNA material pEGFP-C1-mouse centaurin-b2 (RDB15382) , pEGFP-C1-mouse centaurin-b2-R442Q (RDB15383). Comprehensive screening for novel rab-binding proteins by GST pull-down assay using 60 different mammalian Rabs.
DNA material pEGFP-C1-mouse TBC1D2B (RDB14984) , pEGFP-C1-human TBC1D7 (RDB14989) , pEGFP-C1-human TBC1D22B (RDB15010) , pEGFP-C1-human TBCKL (RDB15023) Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.
C.elegans tm3701 , tm1826 , tm1949 Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans.
C.elegans tm3802 , tm2282 , tm3255 TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans.
C.elegans tm2313 , tm399 , tm1075 Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway.
Human and Animal Cells 293T(RCB2202) Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration.