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  • Search Condition : Filter (MeSH = GTPase-Activating Proteins / physiology*)
Species Resource
Yeast FY15527 Fission yeast IQGAP arranges actin filaments into the cytokinetic contractile ring.
C.elegans tm2241 TBC-2 is required for embryonic yolk protein storage and larval survival during L1 diapause in Caenorhabditis elegans.
Drosophila DGRC#104910 Adult neuronal Arf6 controls ethanol-induced behavior with Arfaptin downstream of Rac1 and RhoGAP18B.
C.elegans tm1909 Glia initiate brain assembly through noncanonical Chimaerin-Furin axon guidance in C. elegans.
DNA material pEGFP-C1-human TBC1D1 (RDB14982) , pEGFP-C1-human TBC1D2A (RDB14983) , pEGFP-C1-human TBC1D3 (RDB14985) , pEGFP-C1-human TBC1D4 (RDB14986) , pEGFP-C1-human TBC1D5 (RDB14987) , pEGFP-C1-human TBC1D6 (RDB14988) , pEGFP-C1-human TBC1D8A (RDB14990) , pEGFP-C1-human TBC1D8B (RDB14991) , pEGFP-C1-human TBC1D9A (RDB14992) , pEGFP-C1-human TBC1D9B (RDB14993) , ... Identification of EPI64 as a GTPase-activating protein specific for Rab27A.
DNA material pEF-T7-human TBC1D12 (RDB14978) OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation.
C.elegans tm2328 , tm1447 The Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisions.
DNA material pEGFP-C1-mouse Rab35 (RDB14197) , pEGFP-C1-mouse Rab35(TS/TA) (RDB14198) , pEGFP-C1-mouse Rab35(S5A) (RDB14199). Structure-function analyses of the small GTPase Rab35 and its effector protein centaurin-β2/ACAP2 during neurite outgrowth of PC12 cells.
Drosophila Conundrum, an ARHGAP18 orthologue, regulates RhoA and proliferation through interactions with Moesin.
DNA material pNY24-GLO3 (RDB08549) , pNY24-3HA-GLO3 (RDB08550) , pNY24-GCS1 (RDB08551) , pNY24-GCS1-3HA (RDB08552) , pNY24-GLO3-A-GCS1 (RDB08553) , pNY24-GLO3-N-GCS1 (RDB08554) , pNY24-GCS1-A-GLO3 (RDB08555) , pNY24-GCS1-N-GLO3 (RDB08556) , pNY24-AGE1 (RDB08557) , pNY24-AGE2 (RDB08558) The Arf1p GTPase-activating protein Glo3p executes its regulatory function through a conserved repeat motif at its C-terminus.
Human and Animal Cells DOCK7 is a critical regulator of the RAGE-Cdc42 signaling axis that induces formation of dendritic pseudopodia in human cancer cells.
DNA material pEF-T7-human TBC1D12-N (RDB14979) , pEF-T7-human TBC1D12-M (RDB14980) , pEF-T7-human TBC1D12-TBC (RDB14981) , pEGFP-C1-human TBC1D12-R559K (RDB14999) , pEGFP-C1-human TBC1D28 (RDB15015) , pEGFP-C1-human TBC1D29 (RDB15016) , pGEX-4T-3-mouse Rab11A-Q70L (RDB15028) , pGEX-4T-3-mouse Rab11A-S25N (RDB15029) , pmStr-C1-mouse Rab11A (RDB15030) , pmStr-C1-mouse Rab11A-Q70L (RDB15031) , ... TBC1D12 is a novel Rab11-binding protein that modulates neurite outgrowth of PC12 cells.