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Species Resource Title
Human and Animal Cells JHOC-5(RCB1520) , JHOC-9(RCB2226) MicroRNA-21 is a candidate driver gene for 17q23-25 amplification in ovarian clear cell carcinoma.
Human and Animal Cells TE-1(RCB1894) , TE-9(RCB1988) , TE-11(RCB2100) Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling.
Human and Animal Cells CACO-2(RCB0988) Mitotic checkpoint regulator RAE1 promotes tumor growth in colorectal cancer.
DNA material pdeltaBN.AR1 (RDB18705) Amplification of plasmids containing a mammalian replication initiation region is mediated by controllable conflict between replication and transcription.
DNA material pG5 (RDB18709) Dissection of the beta-globin replication-initiation region reveals specific requirements for replicator elements during gene amplification.
Human and Animal Cells RERF-LC-AI(RCB0444) YES1 Is a Targetable Oncogene in Cancers Harboring YES1 Gene Amplification.
Human and Animal Cells HCE-T(RCB2280) Venetoclax-based Rational Combinations are Effective in Models of MYCN-amplified Neuroblastoma.
Human and Animal Cells MKN45(RCB1001) CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions.
Human and Animal Cells SK-N-SH(RCB0426) Thymidylate synthase inhibitor raltitrexed can induce high levels of DNA damage in MYCN-amplified neuroblastoma cells.
Human and Animal Cells TKKK(RCB1907) , TGBC2TKB(RCB1130) , TGBC18TKB(RCB1169) , TGBC14TKB(RCB1186) , G-415(RCB2640) , HuCCT1(RCB1960) K-Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines.
Human and Animal Cells Ba/F3(RCB0805) Acquired resistance to LY2874455 in FGFR2-amplified gastric cancer through an emergence of novel FGFR2-ACSL5 fusion.
Human and Animal Cells COLO205(RCB2127) , HCT116(RCB2979) Oncogenic splicing abnormalities induced by DEAD-Box Helicase 56 amplification in colorectal cancer.
Drosophila Initiation of Drosophila chorion gene amplification requires Claspin and mus101, whereas Claspin, but not mus101, plays a major role during elongation.
Human and Animal Cells MKN7(RCB0999) , A431 Gene amplification of CCNE1, CCND1, and CDK6 in gastric cancers detected by multiplex ligation-dependent probe amplification and fluorescence in situ hybridization.
DNA material CSII-CMV-RfA-IRES2-Venus (RDB04388) , CSII-CMV-Venus (RDB05553) , CSII-CMV-mRFP (RDB06386). SGO1 is involved in the DNA damage response in MYCN-amplified neuroblastoma cells.
Human and Animal Cells Gene amplification of ZNF217 located at chr20q13.2 is associated with lymph node metastasis in ovarian clear cell carcinoma.
Human and Animal Cells 10T1/2(RCB0247) A selective amplifier gene for tamoxifen-inducible expansion of hematopoietic cells.
Human and Animal Cells JHOC-9(RCB2226) Prognostic and therapeutic impact of the chromosome 20q13.2 ZNF217 locus amplification in ovarian clear cell carcinoma.
Human and Animal Cells JHOC-5(RCB1520) Gene amplification CCNE1 is related to poor survival and potential therapeutic target in ovarian cancer.
Drosophila DGRC#206424 Regulation of pattern formation and gene amplification during Drosophila oogenesis by the miR-318 microRNA.