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  • 検索条件 : 絞込み (MeSH = Guanine Nucleotide Exchange Factors / genetics*)
生物種 リソース名 タイトル
実験動物マウス RBRC02699 Deletion of Rapgef6, a candidate schizophrenia susceptibility gene, disrupts amygdala function in mice.
ゼブラフィッシュ Tg(CM-isl1:GFP)rw0 INPP5K and SIL1 associated pathologies with overlapping clinical phenotypes converge through dysregulation of PHGDH.
線虫 tm2760 , tm5205 , tm2255 , tm6137 Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals.
イネ Induced mutation lines Selective sets of mRNAs localize to extracellular paramural bodies in a rice glup6 mutant.
線虫 tm5597 , tm597 RPM-1 regulates axon termination by affecting growth cone collapse and microtubule stability.
遺伝子材料 pEF-FLAG-mouse VAMP-7 (RDB15173) Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes.
実験動物マウス RBRC02711 The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction.
線虫 tm1512 Disruption of endocytic pathway regulatory genes activates autophagy in C. elegans.
線虫 tm4246 , tm3467 , tm4024 , tm2807 Systematic analyses of rpm-1 suppressors reveal roles for ESS-2 in mRNA splicing in Caenorhabditis elegans.
線虫 tm1447 , tm1877 Inhibition of Cytohesins Protects against Genetic Models of Motor Neuron Disease.
線虫 tm4024 Developmental Function of the PHR Protein RPM-1 Is Required for Learning in Caenorhabditis elegans.
ヒト・動物細胞 Y79(RCB1645) , WERI-Rb-1(RCB2146) RNAi mediated Tiam1 gene knockdown inhibits invasion of retinoblastoma.
ショウジョウバエ Age-dependent deterioration of locomotion in Drosophila melanogaster deficient in the homologue of amyotrophic lateral sclerosis 2.
ショウジョウバエ Reduced cell number in the hindgut epithelium disrupts hindgut left-right asymmetry in a mutant of pebble, encoding a RhoGEF, in Drosophila embryos.
遺伝子材料 pDUAL-YFH1c (RDB06151) , SpYFH30G11 (SPW092155) , SpYFH39H12 (SPW095780) , SpYFH13E01 (SPW085297) , SpYFH36D10 (SPW094482) , SpYFH36G05 (SPW094549). Haploinsufficiency of the Sec7 guanine nucleotide exchange factor gea1 impairs septation in fission yeast.
酵母 CUE domain-containing protein Vps901 is required for vacuolar protein transport in Schizosaccharomyces pombe.
酵母 cDNA libraries Role of guanine nucleotide exchange factors for Rho family GTPases in the regulation of cell morphology and actin cytoskeleton in fission yeast.
実験動物マウス RBRC00209 , RBRC00423 , RBRC00432 Mutation of Dock5, a member of the guanine exchange factor Dock180 superfamily, in the rupture of lens cataract mouse.
線虫 tm920 , tm1320 , tm584 , tm847 , tm935 , tm933 , tm920 , tm246 Genetic analysis of lysosomal trafficking in Caenorhabditis elegans.