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  • 検索条件 : 絞込み (MeSH = Guanine Nucleotide Exchange Factors / physiology*)
生物種 リソース名 タイトル
ヒト・動物細胞 Saos-2(RCB0428) The survival and proliferation of osteosarcoma cells are dependent on the mitochondrial BIG3-PHB2 complex formation.
ヒト・動物細胞 HCE-T(RCB2280) Role of β-Pix in corneal epithelial cell migration on fibronectin.
ショウジョウバエ DGRC#206863 Sec71 functions as a GEF for the small GTPase Arf1 to govern dendrite pruning of Drosophila sensory neurons.
遺伝子材料 pEF-T7-HPS4(S541A/N543A) (RDB17367) , pEF-T7-HPS4(G55W/G59M) (RDB17368) , pEF-FLAG-HPS1 (RDB17369) , pGBD-C1-Rab6D-deltaCys-T45N (RDB17399) , pGBD-C1-Rab40AL-deltaCys-S28N (RDB17444) , pGBD-C1-Rab6D-deltaCys-Q89L (RDB18834) , pGBD-C1-Rab40AL-deltaCys-Q73L (RDB18924) The BLOC-3 subunit HPS4 is required for activation of Rab32/38 GTPases in melanogenesis, but its Rab9 activity is dispensable for melanogenesis.
ヒト・動物細胞 MDCK(RCB0995) Upregulation of multiple signaling pathways by Dock5 deletion in epithelial cells.
遺伝子材料 pEGFP-C1-mouse GRAB (RDB14674) Cdk5 Regulation of the GRAB-Mediated Rab8-Rab11 Cascade in Axon Outgrowth.
線虫 tm3480 RPM-1 uses both ubiquitin ligase and phosphatase-based mechanisms to regulate DLK-1 during neuronal development.
線虫 mec-15(tm2691) , mec-12(tm5083) , cebp-1(tm2807) RHGF-1/PDZ-RhoGEF and retrograde DLK-1 signaling drive neuronal remodeling on microtubule disassembly.
遺伝子材料 CSII-CMV-MCS (RDB04377) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Impaired vascular development in the yolk sac and allantois in mice lacking RA-GEF-1.
線虫 tm920 C. elegans RPM-1 regulates axon termination and synaptogenesis through the Rab GEF GLO-4 and the Rab GTPase GLO-1.