When you enter multiple keywords separated by space, your search will contain results that match any of the keywords (OR search).
  • 9 Hits
  • Search Condition : Filter (MeSH = Huntington Disease / metabolism*)
Species Resource
Drosophila Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73.
Drosophila Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease.
C.elegans tm4397 The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington's disease.
Drosophila 7563R-1 , 18152R-2 Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity.
Mice GFP-LC3#53(RBRC00806) The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.
Drosophila 7459R-2 Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding.
C.elegans fust-1(tm4439) , pgrn-1(tm985) Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models.
Mice GFP-LC3#53 A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model.
C.elegans tm1374 Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity.