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  • 11 Hits
  • 検索条件 : 絞込み (MeSH = Huntington Disease / metabolism*)
生物種 リソース名 タイトル
線虫 tm1108 Identification of Novel Therapeutic Targets for Polyglutamine Diseases That Target Mitochondrial Fragmentation.
ショウジョウバエ 11144R-3 Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.
ショウジョウバエ Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73.
ショウジョウバエ Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease.
線虫 tm4397 The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington's disease.
ショウジョウバエ 7563R-1 , 18152R-2 Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity.
実験動物マウス RBRC00806 The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.
ショウジョウバエ 7459R-2 Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding.
線虫 fust-1(tm4439) , pgrn-1(tm985) Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models.
実験動物マウス RBRC00806 A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model.
線虫 tm1374 Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity.