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  • 31 Hits
  • Search Condition : Filter (MeSH = Hypoxia-Inducible Factor 1, alpha Subunit / metabolism*)
Species Resource Title
Human and Animal Cells Hep G2 Hypoxia accelerates cancer invasion of hepatoma cells by upregulating MMP expression in an HIF-1alpha-independent manner.
Human and Animal Cells THP-1(RCB1189) Hypoxia suppresses stretch-induced elongation and orientation of macrophages.
Human and Animal Cells Saos-2(RCB0428) Transcription factor YY1 contributes to tumor growth by stabilizing hypoxia factor HIF-1α in a p53-independent manner.
Human and Animal Cells COLO-320(RCB1193) HIF-1α activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells.
Human and Animal Cells MKN45(RCB1001) , MKN74(RCB1002) Matrix metalloproteinase‑1 expression is regulated by HIF‑1‑dependent and epigenetic mechanisms and serves a tumor‑suppressive role in gastric cancer progression.
Human and Animal Cells MH7A(RCB1512) Sustained Hypoxia Suppresses Joint Destruction in a Rat Model of Rheumatoid Arthritis via Negative Feedback of Hypoxia Inducible Factor-1α.
Human and Animal Cells TE-1(RCB1894) , TE-8(RCB2098) , TE-15(RCB1951) Nuclear PROX1 is Associated with Hypoxia-Inducible Factor 1α Expression and Cancer Progression in Esophageal Squamous Cell Carcinoma.
Human and Animal Cells WI-38(RCB0702) Antifibrotic effects of cyclosporine A on TGF-β1-treated lung fibroblasts and lungs from bleomycin-treated mice: role of hypoxia-inducible factor-1α.
Human and Animal Cells ATDC5(RCB0565) Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling.
Human and Animal Cells HuH-7 HIF-1α-induced RIT1 promotes liver cancer growth and metastasis and its deficiency increases sensitivity to sorafenib.
Human and Animal Cells EBC-1(RCB1965) Development of single nanometer-sized ultrafine oxygen bubbles to overcome the hypoxia-induced resistance to radiation therapy via the suppression of hypoxia-inducible factor‑1α.
DNA material pCMFlag_hsc-Myc (RDB06671) Cellular density-dependent increases in HIF-1α compete with c-Myc to down-regulate human EP4 receptor promoter activity through Sp-1-binding region.
C.elegans tm2285 Mitochondrial metabolites extend lifespan.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Hypoxic stress upregulates Kir2.1 expression by a pathway including hypoxic-inducible factor-1α and dynamin2 in brain capillary endothelial cells.
Human and Animal Cells HS-Sch-2(RCB2230) Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor.
Human and Animal Cells ATDC5(RCB0565) Nkx3.2 induces oxygen concentration-independent and lysosome-dependent degradation of HIF-1α to modulate hypoxic responses in chondrocytes.
Human and Animal Cells MH7A(RCB1512) Synovial cell death is regulated by TNF-α-induced expression of B-cell activating factor through an ERK-dependent increase in hypoxia-inducible factor-1α.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). Requirement of Hsp105 in CoCl2-induced HIF-1α accumulation and transcriptional activation.
DNA material AxCANCre (RDB01748) Hyaluronan Production Regulates Metabolic and Cancer Stem-like Properties of Breast Cancer Cells via Hexosamine Biosynthetic Pathway-coupled HIF-1 Signaling.
Human and Animal Cells MCF7(RCB1904) The single N-glycan deletion mutant of soluble ErbB3 protein attenuates heregulin β1-induced tumor progression by blocking of the HIF-1 and Nrf2 pathway.