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  • Search Condition : Filter (MeSH = Hypoxia-Inducible Factor 1, alpha Subunit / metabolism*)
Species Resource Title
Human and Animal Cells MKN28(RCB1000) Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A.
Human and Animal Cells Hep G2 Hypoxia accelerates cancer invasion of hepatoma cells by upregulating MMP expression in an HIF-1alpha-independent manner.
Human and Animal Cells THP-1(RCB1189) Hypoxia suppresses stretch-induced elongation and orientation of macrophages.
Human and Animal Cells Saos-2(RCB0428) Transcription factor YY1 contributes to tumor growth by stabilizing hypoxia factor HIF-1α in a p53-independent manner.
Human and Animal Cells COLO-320(RCB1193) HIF-1α activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells.
Human and Animal Cells MKN45(RCB1001) , MKN74(RCB1002) Matrix metalloproteinase‑1 expression is regulated by HIF‑1‑dependent and epigenetic mechanisms and serves a tumor‑suppressive role in gastric cancer progression.
Human and Animal Cells MH7A(RCB1512) Sustained Hypoxia Suppresses Joint Destruction in a Rat Model of Rheumatoid Arthritis via Negative Feedback of Hypoxia Inducible Factor-1α.
Human and Animal Cells TE-1(RCB1894) , TE-8(RCB2098) , TE-15(RCB1951) Nuclear PROX1 is Associated with Hypoxia-Inducible Factor 1α Expression and Cancer Progression in Esophageal Squamous Cell Carcinoma.
Human and Animal Cells WI-38(RCB0702) Antifibrotic effects of cyclosporine A on TGF-β1-treated lung fibroblasts and lungs from bleomycin-treated mice: role of hypoxia-inducible factor-1α.
Human and Animal Cells ATDC5(RCB0565) Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling.
Human and Animal Cells HuH-7 HIF-1α-induced RIT1 promotes liver cancer growth and metastasis and its deficiency increases sensitivity to sorafenib.
Human and Animal Cells EBC-1(RCB1965) Development of single nanometer-sized ultrafine oxygen bubbles to overcome the hypoxia-induced resistance to radiation therapy via the suppression of hypoxia-inducible factor‑1α.
DNA material pCMFlag_hsc-Myc (RDB06671) Cellular density-dependent increases in HIF-1α compete with c-Myc to down-regulate human EP4 receptor promoter activity through Sp-1-binding region.
C.elegans tm2285 Mitochondrial metabolites extend lifespan.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Hypoxic stress upregulates Kir2.1 expression by a pathway including hypoxic-inducible factor-1α and dynamin2 in brain capillary endothelial cells.
Human and Animal Cells HS-Sch-2(RCB2230) Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor.
Human and Animal Cells ATDC5(RCB0565) Nkx3.2 induces oxygen concentration-independent and lysosome-dependent degradation of HIF-1α to modulate hypoxic responses in chondrocytes.
Human and Animal Cells MH7A(RCB1512) Synovial cell death is regulated by TNF-α-induced expression of B-cell activating factor through an ERK-dependent increase in hypoxia-inducible factor-1α.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). Requirement of Hsp105 in CoCl2-induced HIF-1α accumulation and transcriptional activation.
DNA material AxCANCre (RDB01748) Hyaluronan Production Regulates Metabolic and Cancer Stem-like Properties of Breast Cancer Cells via Hexosamine Biosynthetic Pathway-coupled HIF-1 Signaling.