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  • 41 Hits
  • Search Condition : Filter (MeSH = Imidazoles / pharmacology*)
Species Resource Title
Human and Animal Cells MH7A(RCB1512) Enhancement of anti-inflammatory tendency by SB203580, p38alpha specific inhibitor, in human fibroblast-like synoviocyte cell line, MH7A.
Human and Animal Cells LM8(RCB1450) The Thioredoxin-1 Inhibitor, PX-12, Suppresses Local Osteosarcoma Progression.
Human and Animal Cells Hep G2(RCB1648) , HuH-7(RCB1942) Effects of Pyrrole-Imidazole Polyamides Targeting Human TGF-β1 on the Malignant Phenotypes of Liver Cancer Cells.
Human and Animal Cells LM8(RCB1450) Reduction of metastasis, cell invasion, and adhesion in mouse osteosarcoma by YM529/ONO-5920-induced blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathway.
Human and Animal Cells Lu99(RCB1900) Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
Human and Animal Cells HuH-7(RCB1366) Targeting cap-dependent translation to inhibit Chikungunya virus replication: selectivity of p38 MAPK inhibitors to virus-infected cells due to autophagy-mediated down regulation of phospho-ERK.
Human and Animal Cells Hep G2(RCB1648) Growth inhibition by NVP-BEZ235, a dual PI3K/mTOR inhibitor, in hepatocellular carcinoma cell lines.
Human and Animal Cells NIH/3T3(RCB2767) Zoledronic acid suppresses transforming growth factor-β-induced fibrogenesis by human gingival fibroblasts.
Human and Animal Cells 32Dcl3 Functional characterization, localization, and inhibitor sensitivity of the TPR-FGFR1 fusion in 8p11 myeloproliferative syndrome.
Human and Animal Cells TGBC1TKB(RCB1129) , TGBC24TKB(RCB1196) Comparison of γδ T cell responses and farnesyl diphosphate synthase inhibition in tumor cells pretreated with zoledronic acid.
Mice RBRC01361 Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia.
Human and Animal Cells Hep G2 Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR.
Human and Animal Cells MDCK(RCB0995) Canine squamous cell carcinoma cell lines with high expression of survivin are sensitive to survivin inhibitor YM155.
Human and Animal Cells HCT116(RCB2979) SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex.
Human and Animal Cells Li-7(RCB1941) , Hep G2(RCB1648) , T2(RCB1932) , K562 Hepatocellular carcinoma cell sensitivity to Vγ9Vδ2 T lymphocyte-mediated killing is increased by zoledronate.
Zebrafish Tg(6xTcf/LefBS-miniP:d2EGFP) Axitinib blocks Wnt/β-catenin signaling and directs asymmetric cell division in cancer.
Pathogenic microorganisms ? Candida glabrata drug:H+ antiporter CgQdr2 confers imidazole drug resistance, being activated by transcription factor CgPdr1.
Human and Animal Cells Ba/F3(RCB0805) Targeting wild-type and mutationally activated FGFR4 in rhabdomyosarcoma with the inhibitor ponatinib (AP24534).
Human and Animal Cells JHUEM-2(RCB1551) The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors.
Human and Animal Cells Reversible induction of PARP1 degradation by p53-inducible cis-imidazoline compounds.