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  • Search Condition : Filter (MeSH = Inflammasomes / metabolism*)
Species Resource Title
Human and Animal Cells THP-1(RCB1189) The lysosome rupture-activated TAK1-JNK pathway regulates NLRP3 inflammasome activation.
Human and Animal Cells J774.1(RCB0434) GRIM-19 is a target of mycobacterial Zn2+ metalloprotease 1 and indispensable for NLRP3 inflammasome activation.
Human and Animal Cells RAW 264(RCB0535) Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes.
Zebrafish Tg(EF1α:mAG-zGem(1/100)) rw0410h Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production.
Human and Animal Cells J774.1(RCB0434) The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction.
Human and Animal Cells THP-1(RCB1189) Helicobacter pylori induces IL-1β protein through the inflammasome activation in differentiated macrophagic cells.
Human and Animal Cells J774.1(RCB0434) Glucose regulates hypoxia-induced NLRP3 inflammasome activation in macrophages.
DNA material CSII-EF-RfA (RDB04387) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Induced pluripotent stem cell-derived monocytic cell lines from a NOMID patient serve as a screening platform for modulating NLRP3 inflammasome activity.
Human and Animal Cells Colon-26(RCB2657) Caspase-7 mediates caspase-1-induced apoptosis independently of Bid.
Human and Animal Cells Control iPS Functional evaluation of the pathological significance of MEFV variants using induced pluripotent stem cell-derived macrophages.
Human and Animal Cells MG6(RCB2403) Extracellular ADP augments microglial inflammasome and NF-κB activation via the P2Y12 receptor.
DNA material CS-CA-MCS (RDB05963) ARIH2 Ubiquitinates NLRP3 and Negatively Regulates NLRP3 Inflammasome Activation in Macrophages.
Mice RBRC02975 Dietary PUFAs attenuate NLRP3 inflammasome activation via enhancing macrophage autophagy.
Human and Animal Cells 293(RCB1637) CARD8 is a negative regulator for NLRP3 inflammasome, but mutant NLRP3 in cryopyrin-associated periodic syndromes escapes the restriction.
DNA material , Human and Animal Cells CSII-EF-MCS-IRES2-Venus (RDB04384) , pCMV-VSV-G-RSV-Rev (RDB04393). , THP-1(RCB1189) , 293(RCB1637) Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.
Mice RBRC01828 Single-cell imaging of caspase-1 dynamics reveals an all-or-none inflammasome signaling response.
DNA material pCMFlag_hsIL1B (RDB06666). Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.
Mice RBRC01390 Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis.