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  • Search Condition : Filter (MeSH = Kelch-Like ECH-Associated Protein 1 / metabolism*)
Species Resource Title
Drosophila DGRC#107554 , DGRC#101586 , 6343R-1 , 6343R-2 , 2286R-2 The Nrf2-Keap1 pathway is activated by steroid hormone signaling to govern neuronal remodeling.
Human and Animal Cells PC-12(RCB0009) Role of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in mice.
Human and Animal Cells Hepa 1-6(RCB1638) Sp1 is a substrate of Keap1 and regulates the activity of CRL4AWDR23 ubiquitin ligase toward Nrf2.
Mice RBRC01390 Inhibition of the Keap1/Nrf2 Signaling Pathway Significantly Promotes the Progression of Type 1 Diabetes Mellitus.
Mice RBRC01390 Sinomenine protects bone from destruction to ameliorate arthritis via activating p62Thr269/Ser272-Keap1-Nrf2 feedback loop.
Human and Animal Cells Hep G2(RCB1886) Effect of combined exposure to environmental aliphatic electrophiles from plants on Keap1/Nrf2 activation and cytotoxicity in HepG2 cells: A model of an electrophile exposome.
Human and Animal Cells Hep G2(RCB1886) A strategy for repression of arsenic toxicity through nuclear factor E2 related factor 2 activation mediated by the (E)-2-alkenals in Coriandrum sativum L. leaf extract.
Mice RBRC05704 Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1.
Human and Animal Cells 293(RCB1637) Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding.
Human and Animal Cells LK-2(RCB1970) , TGBC24TKB(RCB1196) The discovery and characterization of K-563, a novel inhibitor of the Keap1/Nrf2 pathway produced by Streptomyces sp.
Human and Animal Cells PC-12(RCB0009) Allantopyrone A activates Keap1-Nrf2 pathway and protects PC12 cells from oxidative stress-induced cell death.
Mice RBRC01388 , RBRC01390 Effects of deficiency of Kelch-like ECH-associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic 1 during osteoclastogenesis.