• 7 Hits
  • 検索条件 : 絞込み (MeSH = Lactams, Macrocyclic / pharmacology*)
生物種 リソース名 タイトル
ヒト・動物細胞 Ba/F3(RCB0805) Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer.
ヒト・動物細胞 PC-12(RCB0009) Effects of geldanamycin on neurite outgrowth-related proteins and kinases in nerve growth factor-differentiated pheochromocytoma 12 cells.
ヒト・動物細胞 C2C12(RCB0987) Pharmacological targeting of HSP90 with 17-AAG induces apoptosis of myogenic cells through activation of the intrinsic pathway.
ヒト・動物細胞 G-415(RCB2640) , TGBC1TKB(RCB1129) , TGBC2TKB(RCB1130) , TGBC24TKB(RCB1196) Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.
ヒト・動物細胞 The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway.
ヒト・動物細胞 EBC-1(RCB1965) Enhanced antitumor activity of erlotinib in combination with the Hsp90 inhibitor CH5164840 against non-small-cell lung cancer.
ヒト・動物細胞 ECC4(RCB0982) Low-penetrant RB allele in small-cell cancer shows geldanamycin instability and discordant expression with mutant ras.