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7 Hits
検索条件 : 絞込み (MeSH = Lactams, Macrocyclic / pharmacology*)
生物種
リソース名
RRC ID
タイトル
ジャーナル
公開日
外部リンク
ヒト・動物細胞
Ba/F3(RCB0805)
75789
Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer.
Cancer Discov
2016-10-1
Pubmed
Full text
ヒト・動物細胞
PC-12(RCB0009)
59742
Effects of geldanamycin on neurite outgrowth-related proteins and kinases in nerve growth factor-differentiated pheochromocytoma 12 cells.
J Pharmacol Sci
2019-7-1
Pubmed
Full text
ヒト・動物細胞
C2C12(RCB0987)
52514
Pharmacological targeting of HSP90 with 17-AAG induces apoptosis of myogenic cells through activation of the intrinsic pathway.
Mol Cell Biochem
2018-8-1
Pubmed
Full text
ヒト・動物細胞
G-415(RCB2640)
,
TGBC1TKB(RCB1129)
,
TGBC2TKB(RCB1130)
,
TGBC24TKB(RCB1196)
52125
Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.
Oncotarget
2017-4-18
Pubmed
Full text
ヒト・動物細胞
44788
The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway.
Oncol Rep
2014-2-1
Pubmed
Full text
ヒト・動物細胞
EBC-1(RCB1965)
44533
Enhanced antitumor activity of erlotinib in combination with the Hsp90 inhibitor CH5164840 against non-small-cell lung cancer.
Cancer Sci
2013-10-1
Pubmed
Full text
ヒト・動物細胞
ECC4(RCB0982)
43429
Low-penetrant RB allele in small-cell cancer shows geldanamycin instability and discordant expression with mutant ras.
Cell Cycle
2008-8-1
Pubmed
Full text