• 13 Hits
  • 検索条件 : 絞込み (MeSH = Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy*)
生物種 リソース名 タイトル
ヒト・動物細胞 StromaNKtert(RCB2350) Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia.
ヒト・動物細胞 StromaNKtert(RCB2350) The multi-kinase inhibitor TG02 induces apoptosis and blocks B-cell receptor signaling in chronic lymphocytic leukemia through dual mechanisms of action.
ヒト・動物細胞 DT40(RCB1464) Hypermorphic mutation of phospholipase C, γ2 acquired in ibrutinib-resistant CLL confers BTK independency upon B-cell receptor activation.
ヒト・動物細胞 StromaNKtert(RCB2350) AMG-176, an Mcl-1 Antagonist, Shows Preclinical Efficacy in Chronic Lymphocytic Leukemia.
ヒト・動物細胞 UE6E7T-2(RCB2153) Co-culture of primary CLL cells with bone marrow mesenchymal cells, CD40 ligand and CpG ODN promotes proliferation of chemoresistant CLL cells phenotypically comparable to those proliferating in vivo.
ヒト・動物細胞 StromaNKtert(RCB2350) Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism.
ヒト・動物細胞 StromaNKtert(RCB2350) Bruton's tyrosine kinase inhibition increases BCL-2 dependence and enhances sensitivity to venetoclax in chronic lymphocytic leukemia.
ヒト・動物細胞 9-15C(RCB2323) PKC-β as a therapeutic target in CLL: PKC inhibitor AEB071 demonstrates preclinical activity in CLL.
ヒト・動物細胞 StromaNKtert(RCB2350) Evaluation of bendamustine in combination with fludarabine in primary chronic lymphocytic leukemia cells.
ヒト・動物細胞 UE6E7T-2(RCB2153) Targeting the proliferative and chemoresistant compartment in chronic lymphocytic leukemia by inhibiting survivin protein.
ヒト・動物細胞 KUSA-H1(RCB1990) , 9-15C(RCB2323) , TSt-4(RCB2116) Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration.
ヒト・動物細胞 Influence of bone marrow stromal microenvironment on forodesine-induced responses in CLL primary cells.
ヒト・動物細胞 K562 , Jurkat(RCB0806) CMC-544 (inotuzumab ozogamicin) shows less effect on multidrug resistant cells: analyses in cell lines and cells from patients with B-cell chronic lymphocytic leukaemia and lymphoma.