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Species Resource Title
C.elegans tm4241 Magnolol extends lifespan and improves age-related neurodegeneration in Caenorhabditis elegans via increase of stress resistance.
C.elegans tm1978 S-adenosyl-L-homocysteine extends lifespan through methionine restriction effects.
C.elegans tm311 Immunity-longevity tradeoff neurally controlled by GABAergic transcription factor PITX1/UNC-30.
C.elegans tm1978 Ferulic Acid Supplementation Increases Lifespan and Stress Resistance via Insulin/IGF-1 Signaling Pathway in C. elegans.
C.elegans tm1325 Trimethylamine modulates dauer formation, neurodegeneration, and lifespan through tyra-3/daf-11 signaling in Caenorhabditis elegans.
Yeast BY5701, Strain alias: SH5701, W303-1A S-adenosyl-L-homocysteine extends lifespan through methionine restriction effects.
Yeast FY24018 Genes affecting the extension of chronological lifespan in Schizosaccharomyces pombe (fission yeast).
C.elegans tm6179 , tm1452 , tm1011 Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases.
C.elegans NuRD mediates mitochondrial stress-induced longevity via chromatin remodeling in response to acetyl-CoA level.
C.elegans tm4525 A novel gene-diet interaction promotes organismal lifespan and host protection during infection via the mitochondrial UPR.
Drosophila E-10002 , HK0461.03 , K-S05 , K-S10 , K-S02 Divergence of Drosophila species: Longevity and reproduction under different nutrient balances.
C.elegans tm465 Regulation of lifespan by neural excitation and REST.
C.elegans tm1133 , tm1108 Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans.
C.elegans tm3124 , tm5597 Microtubule regulators act in the nervous system to modulate fat metabolism and longevity through DAF-16 in C. elegans.
C.elegans tm331 XBP-1 Remodels Lipid Metabolism to Extend Longevity.
C.elegans tm1231 , tm2467 Developmental ROS individualizes organismal stress resistance and lifespan.
C.elegans tm2467 SET-9 and SET-26 are H3K4me3 readers and play critical roles in germline development and longevity.
C.elegans tm1145 , tm853 BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans.
Drosophila 2152R-1 , 11561R-2 Hedgehog Signaling Modulates Glial Proteostasis and Lifespan.
Drosophila Loss of BOSS Causes Shortened Lifespan with Mitochondrial Dysfunction in Drosophila.