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Species Resource
Drosophila 5216R-1 , 5216R-2 , 6824R-1 , 6824R-2 , 5085R-3 , 5085R-5 , 6284R-2 , 6284R-4 Involvement of Drosophila Sir2-like genes in the regulation of life span.
C.elegans tm764 Uncoupling of pathways that promote postmitotic life span and apoptosis from replicative immortality of Caenorhabditis elegans germ cells.
C.elegans tm1724 , tm1725 IFTA-2 is a conserved cilia protein involved in pathways regulating longevity and dauer formation in Caenorhabditis elegans.
C.elegans tm776 , tm783 SOD-1 deletions in Caenorhabditis elegans alter the localization of intracellular reactive oxygen species and show molecular compensation.
C.elegans tm869 A novel role for the SMG-1 kinase in lifespan and oxidative stress resistance in Caenorhabditis elegans.
Drosophila DGRC#103877 Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain.
Drosophila A gain-of-function screen to identify genes that reduce lifespan in the adult of Drosophila melanogaster.
Drosophila Longevity determination genes in Drosophila melanogaster.
Drosophila 2020-GAL4 and 6219-GAL4 no pdf available Overexpression of metal-responsive transcription factor (MTF-1) in Drosophila melanogaster ameliorates life-span reductions associated with oxidative stress and metal toxicity.
C.elegans tm4341 Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans.
C.elegans tm776 , tm783 , tm760 , tm1146 , tm1246 Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans.
C.elegans tm2258 Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans.
Drosophila Stock(s) of DGRC Kyoto Pan-neuronal knockdown of the c-Jun N-terminal Kinase (JNK) results in a reduction in sleep and longevity in Drosophila.
C.elegans tm3613 Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.
C.elegans tm1046 Dynamic O-GlcNAc cycling at promoters of Caenorhabditis elegans genes regulating longevity, stress, and immunity.
C.elegans tm1770 Identification of ATF-7 and the insulin signaling pathway in the regulation of metallothionein in C. elegans suggests roles in aging and reactive oxygen species.
C.elegans tm1053 , tm1800 Larval crowding accelerates C. elegans development and reduces lifespan.
C.elegans tm1944 DAF-18/PTEN signals through AAK-1/AMPK to inhibit MPK-1/MAPK in feedback control of germline stem cell proliferation.
C.elegans tm4390 The R148.3 Gene Modulates Caenorhabditis elegans Lifespan and Fat Metabolism.
C.elegans tm1406 , tm1165 Metabotropic GABA signalling modulates longevity in C. elegans.