• 78 Hits
  • 検索条件 : 絞込み (MeSH = Lysosomes / metabolism*)
生物種 リソース名 タイトル
ヒト・動物細胞 THP-1(RCB1189) The lysosome rupture-activated TAK1-JNK pathway regulates NLRP3 inflammasome activation.
線虫 tm3425 Saturated very long chain fatty acid configures glycosphingolipid for lysosome homeostasis in long-lived C. elegans.
遺伝子材料 pMRX-IP-GFP-STX17 (RDB19636) , pMRX-IP-GFP-SNAP29 (RDB19638) , pMRX-IP-GFP-VAMP7 (RDB19639) , pMRX-IP-GFP-VAMP8 (RDB19640) , p3xFLAG-CMV10-Stx17 (RDB19761) , p3xFLAG-CMV10-SNAP29 (RDB19765) , p3xFLAG-CMV10-VAMP7 (RDB19778) , pMRXIP GFP-Stx7 (RDB19779) , pMRXIP-GFP-Stx18 (RDB19792) , pMRXIP-GFP-Stx17TM (RDB19793) The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes.
ゼブラフィッシュ Tg(vglut2a:loxP-DsRed-loxP-GFP) G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
ヒト・動物細胞 201B7(HPS0063) Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease.
遺伝子材料 pMRX-puro-FLAG-hVPS52 (RDB18998) , pMRX-puro-FLAG-hVPS52_N670 (RDB18999) , pMRX-puro-FLAG-hVPS52_N556 (RDB19000) , pMRX-puro-FLAG-hVPS52_N410 (RDB19001) , pMRX-bsr-ss-sfGFP (RDB19002) Knockout analysis of Rab6 effector proteins revealed the role of VPS52 in the secretory pathway.
ヒト・動物細胞 KP4(RCB1005) , PK-1(RCB1972) Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function.
線虫 tm1108 , tm1978 Lysosomal activity regulates Caenorhabditis elegans mitochondrial dynamics through vitamin B12 metabolism.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) , RAW 264(RCB0535) Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88.
ヒト・動物細胞 HuH-7(RCB1366) , CHO-K1(RCB0285) Translocation of the ABC transporter ABCD4 from the endoplasmic reticulum to lysosomes requires the escort protein LMBD1.
ヒト・動物細胞 IMR-90-SV(RCB1024) , Rat-1(RCB1830) Non-thermal plasma induces a stress response in mesothelioma cells resulting in increased endocytosis, lysosome biogenesis and autophagy.
遺伝子材料 pMRX-IP TFEB-sfGFP (RDB18607) , pCW DNAseIIα-sfGFP-T2A-mCherry (RDB18608) Identification of a factor controlling lysosomal homeostasis using a novel lysosomal trafficking probe.
ヒト・動物細胞 Atg5^(-/-)MEF(RCB2711) Sucrose induces vesicle accumulation and autophagy.
ヒト・動物細胞 ST2(RCB0224) Rab27a and Rab27b are involved in stimulation-dependent RANKL release from secretory lysosomes in osteoblastic cells.
遺伝子材料 pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) The Oncogenic PRL Protein Causes Acid Addiction of Cells by Stimulating Lysosomal Exocytosis.
ショウジョウバエ 5520R-1 , 18255R-1 , 31014R-2 , 9726R-1 , 31015R-1 Mislocalization of TORC1 to Lysosomes Caused by KIF11 Inhibition Leads to Aberrant TORC1 Activity.
ショウジョウバエ 31935R-3 The Warburg Micro Syndrome-associated Rab3GAP-Rab18 module promotes autolysosome maturation through the Vps34 Complex I.
遺伝子材料 SRAI_pcDNA3 (RDB18222) , mito-SRAI_pcDNA3 (RDB18223) , pAAV2-TRE-mito-SRAI-BGHpA (RDB18684) , pAAV2-SYN-tTAad-BGHpA (RDB18685) Visualizing and Modulating Mitophagy for Therapeutic Studies of Neurodegeneration.
線虫 tm3425 , tm2508 The RBG-1-RBG-2 complex modulates autophagy activity by regulating lysosomal biogenesis and function in C. elegans.
線虫 tm1978 , tm4324 , tm1974 , tm1954 , tm4498 , tm4417 Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival.