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  • 検索条件 : 絞込み (MeSH = Metalloendopeptidases / metabolism*)
生物種 リソース名 タイトル
ヒト・動物細胞 LoVo(RCB1639) Modulation of matrix metalloproteinase-7 (matrilysin) secretion in coculture of human colon carcinoma cells with fibroblasts from orthotopic and ectopic organs.
ヒト・動物細胞 Kato III(RCB2088) The disintegrin-metalloproteinases ADAM9, ADAM12, and ADAM15 are upregulated in gastric cancer.
遺伝子材料 pClgn1.1 (RDB19247) Calmegin is required for fertilin alpha/beta heterodimerization and sperm fertility.
ヒト・動物細胞 HeLa Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell-cell adhesions in vitro and induces haemorrhage in vivo.
ヒト・動物細胞 MRC-5 Antisense E1AF transfection restrains oral cancer invasion by reducing matrix metalloproteinase activities.
ショウジョウバエ DGRC#108440 IMP regulates Kuzbanian to control the timing of Notch signalling in Drosophila follicle cells.
線虫 tm4525 The Mitochondrial Unfolded Protein Response Protects against Anoxia in Caenorhabditis elegans.
ヒト・動物細胞 293T(RCB2202) Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.
線虫 tm3146 Identification of a novel ADAMTS9/GON-1 function for protein transport from the ER to the Golgi.
線虫 tm2007 The novel secreted factor MIG-18 acts with MIG-17/ADAMTS to control cell migration in Caenorhabditis elegans.
線虫 tm1092 Perlecan antagonizes collagen IV and ADAMTS9/GON-1 in restricting the growth of presynaptic boutons.
線虫 tm3146 , tm1907 , tm2308 Loss of C. elegans GON-1, an ADAMTS9 Homolog, Decreases Secretion Resulting in Altered Lifespan and Dauer Formation.
ヒト・動物細胞 TE-1(RCB1894) , TE-5(RCB1949) , TE-8(RCB2098) , TE-9(RCB1988) , TE-10(RCB2099) , TE-11(RCB2100) NRD1, which encodes nardilysin protein, promotes esophageal cancer cell invasion through induction of MMP2 and MMP3 expression.
ヒト・動物細胞 T24(RCB0431) Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelatinase A in co-cultures with brain-derived fibroblasts.
ヒト・動物細胞 T24(RCB0431) , OST(RCB0454) Enhanced tumor growth and invasiveness in vivo by a carboxyl-terminal fragment of alpha1-proteinase inhibitor generated by matrix metalloproteinases: a possible modulatory role in natural killer cytotoxicity.
ヒト・動物細胞 A431(RCB0202) Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts.
ヒト・動物細胞 MRC-5 Correlated expression of matrix metalloproteinases and ets family transcription factor E1A-F in invasive oral squamous-cell-carcinoma-derived cell lines.
ヒト・動物細胞 T24(RCB0431) Stimulation of TIMP-1 and metalloproteinase production in co-cultures of human tumor cells and human fibroblasts.
遺伝子材料 pEAK-Claudin-5 (RDB02846) Claudin promotes activation of pro-matrix metalloproteinase-2 mediated by membrane-type matrix metalloproteinases.
メダカ Qurt (MT828) An oocyte-specific astacin family protease, alveolin, is released from cortical granules to trigger egg envelope hardening during fertilization in medaka (Oryzias latipes).