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  • Search Condition : Filter (MeSH = Metformin / pharmacology*)
Species Resource Title
Human and Animal Cells iPS-MEF-Ng-20D-17(APS0001) Metformin suppresses self-renewal and stemness of cancer stem cell models derived from pluripotent stem cells.
C.elegans tm1944 , tm3110 BRAF Controls the Effects of Metformin on Neuroblast Cell Divisions in C. elegans.
Human and Animal Cells TGBC14TKB(RCB1186) , TGBC24TKB(RCB1196) Anti-diabetic drug metformin inhibits cell proliferation and tumor growth in gallbladder cancer via G0/G1 cell cycle arrest.
Human and Animal Cells HHUA(RCB0658) Metformin inhibits estrogen-dependent endometrial cancer cell growth by activating the AMPK-FOXO1 signal pathway.
Human and Animal Cells HuH-7 Dreh, a long noncoding RNA repressed by metformin, regulates glucose transport in C2C12 skeletal muscle cells.
C.elegans tm1944 An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer.
Human and Animal Cells PC-9(RCB4455) , A549(RCB0098) Impact of H3K27 Demethylase Inhibitor GSKJ4 on NSCLC Cells Alone and in Combination with Metformin.
Human and Animal Cells PC-9(RCB4455) Drug resistance originating from a TGF-β/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation.
Prokaryotes E. coli Disruption of Hif-1α enhances cytotoxic effects of metformin in murine squamous cell carcinoma.
Human and Animal Cells HuH-7 Metformin inhibits the invasion of human hepatocellular carcinoma cells and enhances the chemosensitivity to sorafenib through a downregulation of the ERK/JNK-mediated NF-κB-dependent pathway that reduces uPA and MMP-9 expression.
Human and Animal Cells RERFLC-AI(RCB0444) , A549(RCB0098) , BALB/3T3 clone A31(RCB0005) Antiproliferative action of metformin in human lung cancer cell lines.
Human and Animal Cells THP-1(RCB1189) Metformin restores impaired HDL-mediated cholesterol efflux due to glycation.
Human and Animal Cells RAW 264(RCB0535) Metformin attenuates production of nitric oxide in response to lipopolysaccharide by inhibiting MyD88-independent pathway.