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  • 33 Hits
  • Search Condition : Filter (MeSH = Mitochondria / genetics*)
Species Resource Title
Human and Animal Cells 293T(RCB2202) Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease.
Drosophila DGRC#112001 Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila.
Human and Animal Cells HeLa Validation of the use of an artificial mitochondrial reporter DNA vector containing a Cytomegalovirus promoter for mitochondrial transgene expression.
C.elegans tm1110 KLF-1 orchestrates a xenobiotic detoxification program essential for longevity of mitochondrial mutants.
C.elegans tm1133 , tm1108 , tm4525 Autophagy compensates for defects in mitochondrial dynamics.
Human and Animal Cells MCF7(RCB1904) , PANC-1(RCB2095) , MIA Paca2(RCB2094) , HCT116(RCB2979) , Hep G2 , HeLa Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction.
Drosophila 3608R-2 Drosophila ADCK1 is critical for maintaining mitochondrial structures and functions in the muscle.
Human and Animal Cells HeLa Mitochondrial transgene expression via an artificial mitochondrial DNA vector in cells from a patient with a mitochondrial disease.
C.elegans tm6724 Activation of DAF-16/FOXO by reactive oxygen species contributes to longevity in long-lived mitochondrial mutants in Caenorhabditis elegans.
C.elegans FAH domain containing protein 1 (FAHD-1) is required for mitochondrial function and locomotion activity in C. elegans.
C.elegans tm4919 , tm1779 , tm598 Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response.
C.elegans tm1779 Affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism.
C.elegans tm3160 , tm5041 Mutations in the Caenorhabditis elegans orthologs of human genes required for mitochondrial tRNA modification cause similar electron transport chain defects but different nuclear responses.
C.elegans tm1359 , tm2807 , tm4248 , tm5421 A conserved mitochondrial surveillance pathway is required for defense against Pseudomonas aeruginosa.
C.elegans tm776 , tm783 , tm760 , tm1146 , tm1246 Mitochondrial and cytoplasmic ROS have opposing effects on lifespan.
C.elegans tm4525 , tm1133 The loss of LRPPRC function induces the mitochondrial unfolded protein response.
Human and Animal Cells Mitochondrial DNA reduced by hypoxic conditions in three-dimensional (3D) spheroid cell cultures.
Zebrafish Tg(brn3a-hsp70:GFP)/rw0110b The cellular and molecular progression of mitochondrial dysfunction induced by 2,4-dinitrophenol in developing zebrafish embryos.
Human and Animal Cells HeLa Dual function MITO-Porter, a nano carrier integrating both efficient cytoplasmic delivery and mitochondrial macromolecule delivery.
Human and Animal Cells MDA-MB-453(RCB1192) Identification of interacting partners of Human Mpv17-like protein with a mitigating effect of mitochondrial dysfunction through mtDNA damage.