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  • Search Condition : Filter (MeSH = Molecular Targeted Therapy*)
Species Resource Title
Human and Animal Cells Ba/F3(RCB0805) Utility of the Ba/F3 cell system for exploring on-target mechanisms of resistance to targeted therapies for lung cancer.
Human and Animal Cells MKN45(RCB1001) Combined drug action of 2-phenylimidazo[2,1-b]benzothiazole derivatives on cancer cells according to their oncogenic molecular signatures.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) , CS-RfA-EVBsd (RDB06090) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Arl4c expression in colorectal and lung cancers promotes tumorigenesis and may represent a novel therapeutic target.
Human and Animal Cells KP4(RCB1005) SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy.
Human and Animal Cells HS-SY-II(RCB2231) Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma.
Human and Animal Cells 293T(RCB2202) Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells.
Human and Animal Cells BOY-12E(RCB2627) , JMSU1(RCB2227) ASP5878, a selective FGFR inhibitor, to treat FGFR3-dependent urothelial cancer with or without chemoresistance.
Human and Animal Cells TGBC2TKB(RCB1130) Targeting the hedgehog pathway for gallbladder cancer therapy?
Human and Animal Cells MKN1(RCB1003) , MKN45(RCB1001) Targeting IRF3 as a YAP agonist therapy against gastric cancer.
Human and Animal Cells TUHR4TKB(RCB1198) , TUHR10TKB(RCB1275) , TUHR14TKB(RCB1383) Modulating ATP binding cassette transporters in papillary renal cell carcinoma type 2 enhances its response to targeted molecular therapy.
Human and Animal Cells GI-1(RCB0763) Chlorotoxin modified morusin-PLGA nanoparticles for targeted glioblastoma therapy.
Human and Animal Cells TGBC2TKB(RCB1130) , TGBC14TKB(RCB1186) , TGBC24TKB(RCB1196) , TGBC18TKB(RCB1169) , TGBC50TKB(RCB1280) , TGBC51TKB(RCB1281) , TGBC52TKB(RCB1282) Molecular targeting of HER2-overexpressing biliary tract cancer cells with trastuzumab emtansine, an antibody-cytotoxic drug conjugate.
Human and Animal Cells Ca9-22(RCB1976) , HSC-2(RCB1945), , HSC-3(RCB1975) , HSC-4(RCB1902) In Vitro Assessment of Antitumor Potential and Combination Effect of Classical and Molecular-targeted Anticancer Drugs.
Human and Animal Cells MDA-MB-453(RCB1192) Therapeutic potential of PLK1 inhibition in triple-negative breast cancer.
Human and Animal Cells StromaNKtert(RCB2350) Bruton's tyrosine kinase inhibition increases BCL-2 dependence and enhances sensitivity to venetoclax in chronic lymphocytic leukemia.
Human and Animal Cells PC-9(RCB4455) The Significance of MMP-1 in EGFR-TKI-Resistant Lung Adenocarcinoma: Potential for Therapeutic Targeting.
Human and Animal Cells TKKK(RCB1907) , TGBC24TKB(RCB1196) , HuCCT1(RCB1960) PI3K-mTOR pathway identified as a potential therapeutic target in biliary tract cancer using a newly established patient-derived cell panel assay.
Human and Animal Cells MKN45(RCB1001) Molecular targeted photoimmunotherapy for HER2-positive human gastric cancer in combination with chemotherapy results in improved treatment outcomes through different cytotoxic mechanisms.
Human and Animal Cells TKKK(RCB1907) Axitinib (AG-013736), an oral specific VEGFR TKI, shows potential therapeutic utility against cholangiocarcinoma.
Human and Animal Cells Identification of a molecular target of a novel fungal metabolite, pyrrolizilactone, by phenotypic profiling systems.