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  • Search Condition : Filter (MeSH = Nerve Degeneration / genetics*)
Species Resource Title
C.elegans tm3310 , tm3360 , tm4059 , tm4910 Mutation of NEKL-4/NEK10 and TTLL genes suppress neuronal ciliary degeneration caused by loss of CCPP-1 deglutamylase function.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain.
C.elegans tm5211 , tm2679 The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival.
Drosophila DGRC#122076 Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.
C.elegans tm805 , tm3036 , tm3117 The Apoptotic Engulfment Machinery Regulates Axonal Degeneration in C. elegans Neurons.
C.elegans tm4255 Neuron-specific knock-down of SMN1 causes neuron degeneration and death through an apoptotic mechanism.
C.elegans tm1817 , tm4995 Mutations in Caenorhabditis elegans neuroligin-like glit-1, the apoptosis pathway and the calcium chaperone crt-1 increase dopaminergic neurodegeneration after 6-OHDA treatment.
C.elegans tm4994 , tm5169 , tm351 , tm4995 Tetraspanin (TSP-17) protects dopaminergic neurons against 6-OHDA-induced neurodegeneration in C. elegans.
C.elegans mec-12(tm5083) Genetic analysis of a novel tubulin mutation that redirects synaptic vesicle targeting and causes neurite degeneration in C. elegans.
C.elegans tm690 , tm858 , tm818 Caenorhabditis elegans glutamate transporter deletion induces AMPA-receptor/adenylyl cyclase 9-dependent excitotoxicity.