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19 Hits
検索条件 : 絞込み (MeSH = Neurodegenerative Diseases / metabolism*)
生物種
リソース名
RRC ID
タイトル
ジャーナル
公開日
外部リンク
ヒト・動物細胞
ASF-4-3L(RCB3580)
77503
A sublethal ATP11A mutation associated with neurological deterioration causes aberrant phosphatidylcholine flipping in plasma membranes.
J Clin Invest
2021-9-15
Pubmed
Full text
線虫
tm1779
76074
Mitochondria-affecting small molecules ameliorate proteostasis defects associated with neurodegenerative diseases.
Sci Rep
2021-9-6
Pubmed
Full text
ヒト・動物細胞
U251(RCB0461)
72295
Expression of alpha-synuclein in a human glioma cell line and its up-regulation by interleukin-1beta.
Neuroreport
2001-7-3
Pubmed
Full text
ショウジョウバエ
2155R-2
,
3757R-5
,
8221R-4
,
8221R-1
64291
Proteasome stress in skeletal muscle mounts a long-range protective response that delays retinal and brain aging.
Cell Metab
2021-6-1
Pubmed
Full text
実験動物マウス
RBRC06334
62271
Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases.
J Neuroinflammation
2020-12-14
Pubmed
Full text
ヒト・動物細胞
KG-1-C(RCB0270)
62044
Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy.
Mol Neurodegener
2012-8-14
Pubmed
Full text
ショウジョウバエ
60789
Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases.
Nat Cell Biol
2007-4-1
Pubmed
Full text
線虫
tm1153
59619
Constitutive XBP-1s-mediated activation of the endoplasmic reticulum unfolded protein response protects against pathological tau.
Nat Commun
2019-9-30
Pubmed
Full text
ヒト・動物細胞
HPS1046
54839
SLC20A2 variants cause dysfunctional phosphate transport activity in endothelial cells induced from Idiopathic Basal Ganglia Calcification patients-derived iPSCs.
Biochem Biophys Res Commun
2019-3-5
Pubmed
Full text
線虫
tm4909
54285
Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity.
Cell
2010-8-20
Pubmed
Full text
線虫
tm1325
,
tm1548
53455
Axotomy-induced HIF-serotonin signalling axis promotes axon regeneration in C. elegans.
Nat Commun
2016-1-21
Pubmed
Full text
実験動物マウス
RBRC01345
49640
Region-specific deletions of the glutamate transporter GLT1 differentially affect seizure activity and neurodegeneration in mice.
Glia
2018-4-1
Pubmed
Full text
ショウジョウバエ
DGRC#105467
47654
A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline.
Neurobiol Dis
2017-2-1
Pubmed
Full text
ショウジョウバエ
13387R-1
,
13387R-4
15591
Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.
Hum Mol Genet
2011-5-1
Pubmed
Full text
ショウジョウバエ
11610
Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones.
J Biol Chem
2008-9-19
Pubmed
Full text
ショウジョウバエ
DGRC#200507
11554
Isolation of gene sets affected specifically by polyglutamine expression: implication of the TOR signaling pathway in neurodegeneration.
Cell Death Differ
2005-8-1
Pubmed
Full text
ショウジョウバエ
310
Phosphorylation of alpha-synuclein characteristic of synucleinopathy lesions is recapitulated in alpha-synuclein transgenic Drosophila.
Neurosci Lett
2003-1-23
Pubmed
Full text
ショウジョウバエ
286
Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.
Neuron
2002-8-29
Pubmed
Full text
ショウジョウバエ
274
Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration.
Cell Death Differ
2002-3-1
Pubmed
Full text