• 19 Hits
  • 検索条件 : 絞込み (MeSH = Neurodegenerative Diseases / metabolism*)
生物種 リソース名 タイトル
ヒト・動物細胞 ASF-4-3L(RCB3580) A sublethal ATP11A mutation associated with neurological deterioration causes aberrant phosphatidylcholine flipping in plasma membranes.
線虫 tm1779 Mitochondria-affecting small molecules ameliorate proteostasis defects associated with neurodegenerative diseases.
ヒト・動物細胞 U251(RCB0461) Expression of alpha-synuclein in a human glioma cell line and its up-regulation by interleukin-1beta.
ショウジョウバエ 2155R-2 , 3757R-5 , 8221R-4 , 8221R-1 Proteasome stress in skeletal muscle mounts a long-range protective response that delays retinal and brain aging.
実験動物マウス RBRC06334 Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases.
ヒト・動物細胞 KG-1-C(RCB0270) Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy.
ショウジョウバエ Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases.
線虫 tm1153 Constitutive XBP-1s-mediated activation of the endoplasmic reticulum unfolded protein response protects against pathological tau.
ヒト・動物細胞 HPS1046 SLC20A2 variants cause dysfunctional phosphate transport activity in endothelial cells induced from Idiopathic Basal Ganglia Calcification patients-derived iPSCs.
線虫 tm4909 Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity.
線虫 tm1325 , tm1548 Axotomy-induced HIF-serotonin signalling axis promotes axon regeneration in C. elegans.
実験動物マウス RBRC01345 Region-specific deletions of the glutamate transporter GLT1 differentially affect seizure activity and neurodegeneration in mice.
ショウジョウバエ DGRC#105467 A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline.
ショウジョウバエ 13387R-1 , 13387R-4 Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.
ショウジョウバエ Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones.
ショウジョウバエ DGRC#200507 Isolation of gene sets affected specifically by polyglutamine expression: implication of the TOR signaling pathway in neurodegeneration.
ショウジョウバエ Phosphorylation of alpha-synuclein characteristic of synucleinopathy lesions is recapitulated in alpha-synuclein transgenic Drosophila.
ショウジョウバエ Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.
ショウジョウバエ Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration.