• 13 Hits
  • 検索条件 : 絞込み (MeSH = Oncogene Proteins, Fusion / metabolism*)
生物種 リソース名 タイトル
研究用ヒト臍帯血幹細胞 The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1.
遺伝子材料 pcDNA3-hRUNX1b (RDB15970) , pcDNA3-hRUNX1b-9KR (RDB15971) The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1.
遺伝子材料 pFLAG-FIP1L1-PDGFRA-FL (RDB15460) , pFLAG-FIP1L1-PDGFRA-KD (RDB15461) , pFLAG-PDGFRA-C (RDB15462) , pCGT-FIP1L1-PDGFRA-FL (RDB15463) , pCGT-FIP1L1-PDGFRA-KD (RDB15464) , pCGT-PDGFRAC (RDB15465). Leukemogenic kinase FIP1L1-PDGFRA and a small ubiquitin-like modifier E3 ligase, PIAS1, form a positive cross-talk through their enzymatic activities.
遺伝子材料 pKM2L-phP21 (RDB05893) ASPL-TFE3 Oncoprotein Regulates Cell Cycle Progression and Induces Cellular Senescence by Up-Regulating p21.
ヒト・動物細胞 MRC-5 Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor resistance in EML4-ALK lung cancer cells.
ヒト・動物細胞 Mechanisms for the proliferation of eosinophilic leukemia cells by FIP1L1-PDGFRalpha.
ヒト・動物細胞 THP-1(RCB1189) Novel role of HDAC inhibitors in AML1/ETO AML cells: activation of apoptosis and phagocytosis through induction of annexin A1.
ヒト・動物細胞 COS-7(RCB0539) SYT-SSX fusion proteins in synovial sarcomas: detection and characterization with new antibodies.
ヒト・動物細胞 Ba/F3(RCB0805) Induction of PD-L1 Expression by the EML4-ALK Oncoprotein and Downstream Signaling Pathways in Non-Small Cell Lung Cancer.
研究用ヒト臍帯血幹細胞 臍帯血 , 研究用ヒト臍帯血幹細胞 Development of a multi-step leukemogenesis model of MLL-rearranged leukemia using humanized mice.
遺伝子材料 pCAG-HIVgp (RDB04394) pCMV-VSV-G-RSV-Rev (RDB04393) pCS-RfA-CG (RDB04390) FIP1L1-PDGFRalpha imposes eosinophil lineage commitment on hematopoietic stem/progenitor cells.
ショウジョウバエ 1765R-2 , 1765R-4 , 7404R-2 , 7404R-3 , 9310R-1 , 9310R-2 , 11783R-1 , 11783R-2 Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model.
ショウジョウバエ A Drosophila model identifies calpains as modulators of the human leukemogenic fusion protein AML1-ETO.