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  • Search Condition : Filter (MeSH = Orphan Nuclear Receptors / metabolism*)
Species Resource Title
Human and Animal Cells RAW 264(RCB0535) Bis(monoacylglycero)phosphate accumulation in macrophages induces intracellular cholesterol redistribution, attenuates liver-X receptor/ATP-Binding cassette transporter A1/ATP-binding cassette transporter G1 pathway, and impairs cholesterol efflux.
Human and Animal Cells RAW 264(RCB0535) Tributyltin chloride induces ABCA1 expression and apolipoprotein A-I-mediated cellular cholesterol efflux by activating LXRα/RXR.
Human and Animal Cells Hep G2 Liver X receptor α bidirectionally transactivates human CYP1A1 and CYP1A2 through two cis-elements common to both genes.
Human and Animal Cells 293(RCB1637) , CACO-2(RCB0988) , MG-63(RCB1890) , SK-N-SH(RCB0426) , HL60(RCB0041) , THP-1(RCB1189) Differential expression and function of alternative splicing variants of human liver X receptor α.
Human and Animal Cells Hep G2 Transport-metabolism interplay: LXRalpha-mediated induction of human ABC transporter ABCC2 (cMOAT/MRP2) in HepG2 cells.
Drosophila UAS-baboRNAi (on X) , 12399R-1 , 12399R-2 , 7904R-2 Drosophila motor neuron retraction during metamorphosis is mediated by inputs from TGF-β/BMP signaling and orphan nuclear receptors.
C.intestinalis / (O.japonicus) Wild C. int Functional diversity of signaling pathways through G protein-coupled receptor heterodimerization with a species-specific orphan receptor subtype.
Mice RBRC01390 Nrf2 inhibits LXRα-dependent hepatic lipogenesis by competing with FXR for acetylase binding.