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Species Resource Title
DNA material pMXs-puro-RFP-ATG9A (RDB19627) , pMRX-IP-SECFP-hATG16L1 (RDB19635) Temporal analysis of recruitment of mammalian ATG proteins to the autophagosome formation site.
DNA material pMRX-IP-GFP-STX17 (RDB19636) , pMRX-IP-GFP-SNAP29 (RDB19638) , pMRX-IP-GFP-VAMP7 (RDB19639) , pMRX-IP-GFP-VAMP8 (RDB19640) , p3xFLAG-CMV10-Stx17 (RDB19761) , p3xFLAG-CMV10-SNAP29 (RDB19765) , p3xFLAG-CMV10-VAMP7 (RDB19778) , pMRXIP GFP-Stx7 (RDB19779) , pMRXIP-GFP-Stx18 (RDB19792) , pMRXIP-GFP-Stx17TM (RDB19793) The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes.
DNA material pEGFP-C1-hATG2A (RDB19631) Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets.
DNA material pMXs-puro-GFP-p62 (RDB19628) , pMXs-IP-GFP-NBR1 (RDB19629) , pMXs-puro-GFP-p62 K7A, D69A (RDB19794) , pMXs-puro-GFP-p62 D337, 338, 339A (RDB19796) , pMXs-puro GFP-p62 dC (RDB20245) p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding.
DNA material pMXs-IP-GFP-WIPI1 (RDB19630) , pMXs-puro-GFP-DFCP1 (RDB19637) , pMXs-IP spGFP-ERGIC53 (RDB19768) , pMXs-puro HA-WIPI-1 (RDB19788) Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins.
DNA material pMXs-IP-EGFP-hFIP200 (RDB19623) , pMXs-IP-EGFP-mAtg5 (RDB19634) , p3xFLAG-CMV10-hFIP200 (RDB19762) , pMXs-IP-EGFP-ULK1(K46N) (RDB19780) , pMXs-IP-EGFP-LC3 (RDB20244) FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.
Human and Animal Cells J774.1 SNAP-23 regulates phagosome formation and maturation in macrophages.
Human and Animal Cells Rat-1(RCB1830) , HeLa(RCB0007) , MCF7(RCB1904) , Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Detection of WIPI1 mRNA as an indicator of autophagosome formation.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Autophagosomal IkappaB alpha degradation plays a role in the long term control of tumor necrosis factor-alpha-induced nuclear factor-kappaB (NF-kappaB) activity.
Zebrafish RIKEN WT Real-time functional analysis of Hv1 channel in neutrophils: a new approach from zebrafish model.
C.elegans tm3489 , tm5755 , tm2423 , tm847 , tm2253 Autophagy mediates phosphatidylserine exposure and phagosome degradation during apoptosis through specific functions of GABARAP/LGG-1 and LC3/LGG-2.
Human and Animal Cells J774.1 Phosphorylation of SNAP-23 at Ser95 causes a structural alteration and negatively regulates Fc receptor-mediated phagosome formation and maturation in macrophages.
C.elegans tm2214 , tm2423 EFF-1 fusogen promotes phagosome sealing during cell process clearance in Caenorhabditis elegans.
C.elegans tm2692 , tm3066 , tm3546 Ubiquitination of the PI3-kinase VPS-34 promotes VPS-34 stability and phagosome maturation.
DNA material pEF-T7-mouse Atg5 (RDB15374) , pEF-T7-mouse Atg12 (RDB15375) , pEF-T7-mouse Atg16L1gamma (RDB15376) , pEGFP-C1-mouse Rab33A (RDB15378) , pEGFP-C1-mouse Rab33B (RDB15379) , pEGFP-C1-mouse Rab33B-Q92L (RDB15380) , pEGFP-C1-mouse Rab33B-T47N (RDB15381). Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation.
Mice RBRC03941 Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells.
C.elegans tm847 , tm3790 , tm1320 , tm2423 , tm1523 Retromer is required for apoptotic cell clearance by phagocytic receptor recycling.
C.elegans tm2095 Sequential action of Caenorhabditis elegans Rab GTPases regulates phagolysosome formation during apoptotic cell degradation.
C.elegans tm3489 The autophagosomal protein LGG-2 acts synergistically with LGG-1 in dauer formation and longevity in C. elegans.
C.elegans tm3425 The WD40 repeat PtdIns(3)P-binding protein EPG-6 regulates progression of omegasomes to autophagosomes.