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  • Search Condition : Filter (MeSH = Phosphatidylinositol 3-Kinases / antagonists & inhibitors)
Species Resource
Human embryonic stem cells KhES-1 , KhES-3 Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling.
Silkworms Transgenic silkworms expressing human insulin receptors for evaluation of therapeutically active insulin receptor agonists.
General Microbes JCM 1612 Candida albicans and Candida parapsilosis rapidly up-regulate galectin-3 secretion by human gingival epithelial cells.
C.elegans tm1888 Insulin/IGF-1 signaling, including class II/III PI3Ks, β-arrestin and SGK-1, is required in C. elegans to maintain pharyngeal muscle performance during starvation.
Xenopus tropicalis Transgenic Xenopus with prx1 limb enhancer reveals crucial contribution of MEK/ERK and PI3K/AKT pathways in blastema formation during limb regeneration.
Medaka OK-Cab (MT830) , Qurt(MT828) Migration of mesenchymal cell fated to blastema is necessary for fish fin regeneration.
Cellular slime molds S00007 Role of phosphatidylinositol 3' kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium.
Human and Animal Cells JHUEM-2(RCB1551) PI3K Inhibitors Synergize with FGFR Inhibitors to Enhance Antitumor Responses in FGFR2mutant Endometrial Cancers.
Human and Animal Cells Acidic pH increases cGMP accumulation through the OGR1/phospholipase C/Ca(2+)/neuronal NOS pathway in N1E-115 neuronal cells.
Human and Animal Cells Examination of a Viral Infection Mimetic Model in Human iPS Cell-Derived Insulin-Producing Cells and the Anti-Apoptotic Effect of GLP-1 Analogue.
Human and Animal Cells RERF-LC-AI(RCB0444) , IA-LM(RCB0554) , WA-hT(RCB2279) Claudin-18 inhibits cell proliferation and motility mediated by inhibition of phosphorylation of PDK1 and Akt in human lung adenocarcinoma A549 cells.
Human and Animal Cells HHUA(RCB0658) Lipocalin 2 Enhances Migration and Resistance against Cisplatin in Endometrial Carcinoma Cells.
Human and Animal Cells Induction of PD-L1 Expression by the EML4-ALK Oncoprotein and Downstream Signaling Pathways in Non-Small Cell Lung Cancer.
Human and Animal Cells Quercetin Decreases Claudin-2 Expression Mediated by Up-Regulation of microRNA miR-16 in Lung Adenocarcinoma A549 Cells.
Human and Animal Cells Induction of UGT1A1 and CYP2B6 by an antimitogenic factor in HepG2 cells is mediated through suppression of cyclin-dependent kinase 2 activity: cell cycle-dependent expression.
Human and Animal Cells MH7A(RCB1512) Cucurbitacin E inhibits TNF-α-induced inflammatory cytokine production in human synoviocyte MH7A cells via suppression of PI3K/Akt/NF-κB pathways.
Human and Animal Cells Decreased mitochondrial apoptotic priming underlies stroma-mediated treatment resistance in chronic lymphocytic leukemia.
Human and Animal Cells PI3K pathway dependencies in endometrioid endometrial cancer cell lines.
Human and Animal Cells Exhaustive exercise increases the TNF-α production in response to flagellin via the upregulation of toll-like receptor 5 in the large intestine in mice.
Human and Animal Cells THP-1 (RCB1189) Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species.