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  • Search Condition : Filter (MeSH = Phosphatidylinositol Phosphates / metabolism*)
Species Resource Title
Drosophila DGRC#108068 A positive feedback loop between Flower and PI(4,5)P2 at periactive zones controls bulk endocytosis in Drosophila.
Human and Animal Cells DT40(RCB1464) Phosphatidylinositol Monophosphates Regulate Optimal Vav1 Signaling Output.
Human and Animal Cells DU145(RCB2143) , PC-3(RCB2145) , 293(RCB1637) , LNCap.FGC(RCB2144) Increased fatty acyl saturation of phosphatidylinositol phosphates in prostate cancer progression.
Human and Animal Cells HeLa SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes.
C.elegans tm3855 , tm5210 , tm5202 , tm1125 , tm2241 , tm4475 , tm327 , tm2253 , tm3171 Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.
Yeast BY21465(YPH250) , BY23849(BY4741) , BY3896(SEY6210) , BYP1419 Phosphatidylinositol 3,5-bisphosphate is involved in methylglyoxal-induced activation of the Mpk1 mitogen-activated protein kinase cascade in Saccharomyces cerevisiae.
C.elegans tm3536 , tm3645 Depletion of mboa-7, an enzyme that incorporates polyunsaturated fatty acids into phosphatidylinositol (PI), impairs PI 3-phosphate signaling in Caenorhabditis elegans.
C.elegans tm1125 , tm3733 , tm2036 , tm246 Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis.
C.elegans tm4475 PI3P phosphatase activity is required for autophagosome maturation and autolysosome formation.
C.elegans tm2423 PtdIns(4,5)P₂ and PtdIns3P coordinate to regulate phagosomal sealing for apoptotic cell clearance.
Cellular slime molds G90237 , G90238 , G90239 , G90240 , G90241 , G90242 , G90243 , G90244 , G90245 , G90246 , ... Phosphoinositide-dependent protein kinase (PDK) activity regulates phosphatidylinositol 3,4,5-trisphosphate-dependent and -independent protein kinase B activation and chemotaxis.
Cellular slime molds S00005 Tumor suppressor PTEN mediates sensing of chemoattractant gradients.
Cellular slime molds G01887 Myosin I links PIP3 signaling to remodeling of the actin cytoskeleton in chemotaxis.
C.elegans tm3171 Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns(3)P critical for the degradation of apoptotic cells.
Yeast ? A novel phosphatidylinositol(3,4,5)P3 pathway in fission yeast.
C.elegans tm2423 , tm847 , tm3790 , tm3221 , tm1595 , tm389 , tm3806 , tm1555 , tm702 , tm1886 , ... Three sorting nexins drive the degradation of apoptotic cells in response to PtdIns(3)P signaling.
Human and Animal Cells DT40(RCB1464) , IP3R^(-) DT40(RCB1467) Role of the phospholipase C-inositol 1,4,5-trisphosphate pathway in calcium release-activated calcium current and capacitative calcium entry.
Arabidopsis / Cultured plant cells, genes sja05800 An Arabidopsis hydrophilic Ca2(+) -binding protein with a PEVK-rich domain, PCaP2, is associated with the plasma membrane and interacts with calmodulin and phosphatidylinositol phosphates.
Yeast ? Role of phosphatidylinositol 3-phosphate in formation of forespore membrane in Schizosaccharomyces pombe.
Yeast FY9906(TP4-1D) Sorting nexin homologues are targets of phosphatidylinositol 3-phosphate in sporulation of Schizosaccharomyces pombe.