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論文 - 一覧

  • 21 Hits
  • 検索条件 : 絞込み (MeSH = Phosphoinositide-3 Kinase Inhibitors*)
生物種 リソース名 タイトル
ヒト・動物細胞 Lu-134-A(RCB0466) , Lu-134-B(RCB0467) Targeting small cell lung cancer harboring PIK3CA mutation with a selective oral PI3K inhibitor PF-4989216.
ヒト・動物細胞 MDCK(RCB0995) Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death.
ヒト・動物細胞 JHOM-1(RCB1676) , JHOM-2B(RCB1682) Dual inhibition of phosphatidylinositol 3'-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach for mucinous adenocarcinoma of the ovary.
ヒト・動物細胞 KUSA-H1(RCB1990) , 9-15C(RCB2323) , UV♀2(RCB1994) , StromaNKtert(RCB2350) The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells.
ヒト・動物細胞 HSC-2(RCB1945) ERK-dependent IL-6 autocrine signaling mediates adaptive resistance to pan-PI3K inhibitor BKM120 in head and neck squamous cell carcinoma.
ヒト・動物細胞 MKN45(RCB1001) , MKN74(RCB1002) Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil.
ヒト・動物細胞 Hep G2 (-)-Epigallocatechin-3-gallate Down-regulates Doxorubicin-induced Overexpression of P-glycoprotein Through the Coordinate Inhibition of PI3K/Akt and MEK/ERK Signaling Pathways.
ヒト・動物細胞 JHOC-5(RCB1520) , JHOC-7(RCB1688) , JHOC-9(RCB2226) , JHOM-1(RCB1676) , JHOS-3(RCB1546) Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition.
ヒト・動物細胞 Hep G2(RCB1648) Growth inhibition by NVP-BEZ235, a dual PI3K/mTOR inhibitor, in hepatocellular carcinoma cell lines.
ヒト・動物細胞 A431(RCB0202) , RAW 264(RCB0535) Invention of a novel photodynamic therapy for tumors using a photosensitizing PI3K inhibitor.
ヒト・動物細胞 JHOC-7(RCB1688) Anti-tumor activity of dual inhibition of phosphatidylinositol 3-kinase and MDM2 against clear cell ovarian carcinoma.
ヒト・動物細胞 StromaNKtert(RCB2350) The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL.
ヒト・動物細胞 JHOC-7(RCB1688) , JHOC-9(RCB2226) , HTOA(RCB0692) , JHOS-2(RCB1521) , JHOS-3(RCB1546) , JHOS-4(RCB1678) Antitumor activity and induction of TP53-dependent apoptosis toward ovarian clear cell adenocarcinoma by the dual PI3K/mTOR inhibitor DS-7423.
ヒト・動物細胞 Synergistic growth inhibition by acyclic retinoid and phosphatidylinositol 3-kinase inhibitor in human hepatoma cells.
ヒト・動物細胞 OCUB-F(RCB0882) mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer.
ヒト・動物細胞 MRC-5 Transient PI3K inhibition induces apoptosis and overcomes HGF-mediated resistance to EGFR-TKIs in EGFR mutant lung cancer.
ヒト・動物細胞 NB19(RCB0479) Targeting PI3K in neuroblastoma.
ヒト・動物細胞 ACC-MESO-1(RCB2292) , ACC-MESO-4(RCB2293) Inhibition of autophagy sensitizes malignant pleural mesothelioma cells to dual PI3K/mTOR inhibitors.
ヒト・動物細胞 A172(RCB2530) Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells.
ヒト・動物細胞 LM8(RCB1450) Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma.