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  • Search Condition : Filter (MeSH = Proteasome Endopeptidase Complex / metabolism*)
Species Resource
Yeast YAT3507 (=BY24003) The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome.
Rats Involvement of Ca2+-dependent proteasome in the degradation of both cyclin B1 and Mos during spontaneous activation of matured rat oocytes.
C.elegans tm544 , tm659 A conserved role of Caenorhabditis elegans CDC-48 in ER-associated protein degradation.
C.elegans tm1180 , tm1349 , tm911 Proteasomal ubiquitin receptor RPN-10 controls sex determination in Caenorhabditis elegans.
Drosophila 4523R-4 , 7356R-1 PINK1 phosphorylates transglutaminase 2 and blocks its proteasomal degradation.
DNA material Genome Network Project Clone IRAL038I16 (HGY095408) Cereblon is recruited to aggresome and shows cytoprotective effect against ubiquitin-proteasome system dysfunction.
DNA material CSII-CMV-MCS (RDB04377) FBXO21 mediates the ubiquitylation and proteasomal degradation of EID1.
Human and Animal Cells Nucleolar stress induces ubiquitination-independent proteasomal degradation of PICT1 protein.
Drosophila Identifying USPs regulating immune signals in Drosophila: USP2 deubiquitinates Imd and promotes its degradation by interacting with the proteasome.
Silkworms NA Role of the ubiquitin-proteasome system in Bombyx mori nucleopolyhedrovirus infection.
Yeast FY7507 , FY12697(L972 )? , FY10254(MY2354) , FY8437(MY566) , FY11440(MY3517) , FY11208(MY3285) , FY8476(MY624) , FY11159(MY3236) , FY11203(MY3280) Nuclear protein quality is regulated by the ubiquitin-proteasome system through the activity of Ubc4 and San1 in fission yeast.
Drosophila 1090R-1 , 1109R-1 , 1443R-1 , 1763R-2 , 1852R-2 , 1973R-2 , 2023R-1 , 2221R-3 , 2711R-1 , 2848R-1 , ... Identification of proteasome components required for apical localization of Chaoptin using functional genomics.
Yeast BYP1805 , BYP1804 A stalled retrotranslocation complex reveals physical linkage between substrate recognition and proteasomal degradation during ER-associated degradation.
Zebrafish ? Vimentin regulates scribble activity by protecting it from proteasomal degradation.
Zebrafish RIKEN WT , SAGFF(LF)168A The ubiquitin proteasome system is required for cell proliferation of the lens epithelium and for differentiation of lens fiber cells in zebrafish.
Human and Animal Cells Cadmium interferes with the degradation of ATF5 via a post-ubiquitination step of the proteasome degradation pathway.
Cellular slime molds G02276 Characterization of a REG/PA28 proteasome activator homolog in Dictyostelium discoideum indicates that the ubiquitin- and ATP-independent REGgamma proteasome is an ancient nuclear protease.
Drosophila Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process.
Arabidopsis / Cultured plant cells, genes rpc00008 The 26S proteasome function and Hsp90 activity involved in the regulation of HsfA2 expression in response to oxidative stress.
Human and Animal Cells Apigenin, chrysin, and luteolin selectively inhibit chymotrypsin-like and trypsin-like proteasome catalytic activities in tumor cells.