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  • Search Condition : Filter (MeSH = Proteasome Endopeptidase Complex / metabolism*)
Species Resource Title
C.elegans tm4525 Proteasome activity contributes to pro-survival response upon mild mitochondrial stress in Caenorhabditis elegans.
DNA material pMXs-IP-HA-Parkin (RDB19764) , pMXs-IP-GFP-Omp25 (RDB19786) Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane.
Human and Animal Cells ST2(RCB0224) Mechanisms involved in suppression of osteoclast supportive activity by transforming growth factor-β1 via the ubiquitin-proteasome system.
Human and Animal Cells Lu99(RCB1900) Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation.
Human and Animal Cells Hep G2 Bortezomib-resistance is associated with increased levels of proteasome subunits and apoptosis-avoidance.
Human and Animal Cells Jurkat Effects of Hydroxy Groups in the A-Ring on the Anti-proteasome Activity of Flavone.
Human and Animal Cells HCT116(RCB2979) The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction.
Human and Animal Cells ACC-MESO-1(RCB2292) , ACC-MESO-4(RCB2293) Proteasomal degradation of polycomb-group protein CBX6 confers MMP-2 expression essential for mesothelioma invasion.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62.
Drosophila Dysfunction of different cellular degradation pathways contributes to specific β-amyloid42-induced pathologies.
DNA material pFLAG-CMV-5a-RPL23 (RDB17324) , pGEX6P-1-RPL23 (RDB17325) , pET-28a-RPL23 (RDB17326) , pCLH'CX-His-T7-RPL23 (RDB17327) , pCMV-GRWD1 (RDB17328) GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.
Human and Animal Cells RPMI8226(RCB3010) Ridaifen-F conjugated with cell-penetrating peptides inhibits intracellular proteasome activities and induces drug-resistant cell death.
Drosophila 4097R–1 , 4097R-2 Proteasome activity determines pupation timing through the degradation speed of timer molecule Blimp-1.
Mice RBRC03928 , RBRC03950 Restricted Expression of the Thymoproteasome Is Required for Thymic Selection and Peripheral Homeostasis of CD8+ T Cells.
C.elegans tm1779 , tm598 A bacterial metabolite induces glutathione-tractable proteostatic damage, proteasomal disturbances, and PINK1-dependent autophagy in C. elegans.
C.elegans tm2777 , tm1968 HSF-1 activates the ubiquitin proteasome system to promote non-apoptotic developmental cell death in C. elegans.
C.elegans tm1180 Graded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome Pathway.
C.elegans tm1743 Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1.
Yeast BYP7430 (pMK151) , BYP7431 (pMK153) , pNHK36: OsTIR1 cDNA In Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-Linked Chain Specificity of the Proteasome.
DNA material pDUAL (RDB06178) Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporation.