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Species Resource Title
Yeast FY21033 The Hsp90 cochaperone TTT promotes cotranslational maturation of PIKKs prior to complex assembly.
C.elegans tm2807 Tribbles pseudokinase NIPI-3 regulates intestinal immunity in Caenorhabditis elegans by controlling SKN-1/Nrf activity.
Human and Animal Cells M4(RCB1611) Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues.
DNA material pENTR4-H1 (RDB04395) Src family kinases promote silencing of ATR-Chk1 signaling in termination of DNA damage checkpoint.
DNA material PINK1_WT-IRES-GFP-NLS (RDB18946) , PINK1_KD-IRES-GFP-NLS (RDB18947) , MUL1_WT-IRES-GFP-NLS (RDB18948) , MUL1_LD-IRES-GFP-NLS (RDB18949) Gemcitabine induces Parkin-independent mitophagy through mitochondrial-resident E3 ligase MUL1-mediated stabilization of PINK1.
Yeast A complex network of interactions between mitotic kinases, phosphatases and ESCRT proteins regulates septation and membrane trafficking in S. pombe.
Human and Animal Cells HeLa , 293T(RCB2202) , HSC-2(RCB1945) , A549 microRNA-203 suppresses invasion and epithelial-mesenchymal transition induction via targeting NUAK1 in head and neck cancer.
Human and Animal Cells ATDC5(RCB0565) Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.
C.elegans tm1133 , tm1108 Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans.
C.elegans tm1779 , tm4525 Compromised Mitochondrial Protein Import Acts as a Signal for UPRmt.
Drosophila Rap1, Canoe and Mbt cooperate with Bazooka to promote zonula adherens assembly in the fly photoreceptor.
Drosophila 3608R-2 Drosophila ADCK1 is critical for maintaining mitochondrial structures and functions in the muscle.
Drosophila 1388R-2 , 7393R-1 Lic regulates JNK-mediated cell death in Drosophila.
Drosophila 1388R-2 MKK3 modulates JNK-dependent cell migration and invasion.
Yeast pRS316[GFPATG8], pRS416GAL1[ATG13], pRS416GAL1[ATG13-8SA], pRS315[mCherry-ATG8] PP2C phosphatases promote autophagy by dephosphorylation of the Atg1 complex.
Drosophila 3051R-1 , 3051R-2 , 11871R-1 , 6715R-3 , 6715R-7 Drosophila LKB1 is required for the assembly of the polarized actin structure that allows spermatid individualization.
Prokaryotes E. coli Phosphorelay of non-orthodox two component systems functions through a bi-molecular mechanism in vivo: the case of ArcB.
C.elegans tm3972 , tm5187 , tm301 Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication.
C.elegans tm2807 , tm4248 Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caenorhabditis elegans intestinal immune surveillance pathway.
C.elegans tm4397 IMPACT is a GCN2 inhibitor that limits lifespan in Caenorhabditis elegans.