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  • Search Condition : Filter (MeSH = Protein Phosphatase 2 / metabolism*)
Species Resource
Human and Animal Cells K562 TOPK is regulated by PP2A and BCR/ABL in leukemia and enhances cell proliferation.
Human and Animal Cells 10T1/2(RCB0247) Reduction of protein phosphatase 2A Cα promotes in vivo bone formation and adipocyte differentiation.
Human and Animal Cells MC3T3-E1(RCB1126) , LM8(RCB1450) Protein phosphatase 2A Cα regulates proliferation, migration, and metastasis of osteosarcoma cells.
Human and Animal Cells HeLa(RCB3680) A regulatory subunit of protein phosphatase 2A, PPP2R5E, regulates the abundance of microtubule crosslinking factor 1.
Yeast BY9943 (SCU2422) Orchestrated Action of PP2A Antagonizes Atg13 Phosphorylation and Promotes Autophagy after the Inactivation of TORC1.
C.elegans tm395 , tm655 Protein phosphatase 2A-SUR-6/B55 regulates centriole duplication in C. elegans by controlling the levels of centriole assembly factors.
C.elegans tm3951 PP2A phosphatase acts upon SAS-5 to ensure centriole formation in C. elegans embryos.
Human and Animal Cells Protein phosphatase 2A Cα is involved in osteoclastogenesis by regulating RANKL and OPG expression in osteoblasts.
Human and Animal Cells Regulated interaction of protein phosphatase 1 and protein phosphatase 2A with phospholipase C-related but catalytically inactive protein.
Yeast ZDS1 , IGO2 plasmids Comparative genetic analysis of PP2A-Cdc55 regulators in budding yeast.
DNA material pLL3.7 K122 FH-TAZ-ires-GFP-TEAD-responsive-H2B mCherry (RDB13967) , pFLAG-human yes-associated protein (YAP)1 (RDB13968) , pClneoMyc-LATS1 (RDB13969) , pClneoMyc-LATS2 (RDB13970) , pClneoLuc-PP1A (RDB13971) , pClneoLuc-PP2A (RDB13972). A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.
Yeast BY4741 , BY4742 , BYP5216 Zds1/Zds2-PP2ACdc55 complex specifies signaling output from Rho1 GTPase.
Yeast BYP1613(ZDS1) Nuclear PP2A-Cdc55 prevents APC-Cdc20 activation during the spindle assembly checkpoint.
Arabidopsis / Cultured plant cells, genes pda08867 , pda09531 , pda12358 Phosphatidic acid (PA) binds PP2AA1 to regulate PP2A activity and PIN1 polar localization.
Human and Animal Cells MC3T3-E1 (RCB1126) Reduction of protein phosphatase 2A Cα enhances bone formation and osteoblast differentiation through the expression of bone-specific transcription factor Osterix.
Arabidopsis / Cultured plant cells, genes pda08867 Specificity of RCN1-mediated protein phosphatase 2A regulation in meristem organization and stress response in roots.