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  • 検索条件 : 絞込み (MeSH = Protein Phosphatase 2 / metabolism*)
生物種 リソース名 タイトル
ヒト・動物細胞 SH-10-TC(RCB1940) Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer.
遺伝子材料 CSII-EF-MCS-IRES2-Venus (RDB04384) , CSII-EF-MCS-IRES2-hKO1 (RDB07915) , pENTR4-H1tetOx1 (RDB07916) , CS-RfA-ETBsd (RDB07917) Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2.
ヒト・動物細胞 K562 TOPK is regulated by PP2A and BCR/ABL in leukemia and enhances cell proliferation.
線虫 tm3103 , tm752 Protein phosphatase 2A is crucial for sarcomere organization in Caenorhabditis elegans striated muscle.
ヒト・動物細胞 MC3T3-E1(RCB1126) Regulation of NF-kB Signalling Through the PR55β-RelA Interaction in Osteoblasts.
ヒト・動物細胞 NIH3T3-3-4(RCB1862) Control of cell migration by the novel protein phosphatase-2A interacting protein inka2.
ヒト・動物細胞 MC3T3-E1(RCB1126) Inhibition of protein phosphatase 2A attenuates titanium-particle induced suppression of bone formation.
ヒト・動物細胞 10T1/2(RCB0247) Reduction of protein phosphatase 2A Cα promotes in vivo bone formation and adipocyte differentiation.
ヒト・動物細胞 MC3T3-E1(RCB1126) , LM8(RCB1450) Protein phosphatase 2A Cα regulates proliferation, migration, and metastasis of osteosarcoma cells.
ヒト・動物細胞 HeLa(RCB3680) A regulatory subunit of protein phosphatase 2A, PPP2R5E, regulates the abundance of microtubule crosslinking factor 1.
酵母 BY9943 (SCU2422) Orchestrated Action of PP2A Antagonizes Atg13 Phosphorylation and Promotes Autophagy after the Inactivation of TORC1.
線虫 tm395 , tm655 Protein phosphatase 2A-SUR-6/B55 regulates centriole duplication in C. elegans by controlling the levels of centriole assembly factors.
線虫 tm3951 PP2A phosphatase acts upon SAS-5 to ensure centriole formation in C. elegans embryos.
ヒト・動物細胞 RAW 264(RCB0535) Protein phosphatase 2A Cα is involved in osteoclastogenesis by regulating RANKL and OPG expression in osteoblasts.
ヒト・動物細胞 Regulated interaction of protein phosphatase 1 and protein phosphatase 2A with phospholipase C-related but catalytically inactive protein.
酵母 ZDS1 , IGO2 plasmids Comparative genetic analysis of PP2A-Cdc55 regulators in budding yeast.
遺伝子材料 pLL3.7 K122 FH-TAZ-ires-GFP-TEAD-responsive-H2B mCherry (RDB13967) , pFLAG-human yes-associated protein (YAP)1 (RDB13968) , pClneoMyc-LATS1 (RDB13969) , pClneoMyc-LATS2 (RDB13970) , pClneoLuc-PP1A (RDB13971) , pClneoLuc-PP2A (RDB13972). A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.
酵母 BYP5216 , BY4741 , BY4742 Zds1/Zds2-PP2ACdc55 complex specifies signaling output from Rho1 GTPase.
酵母 BYP1613(ZDS1) Nuclear PP2A-Cdc55 prevents APC-Cdc20 activation during the spindle assembly checkpoint.
ショウジョウバエ tws02414 (DGRC#108872). The Ser/Thr phosphatase PP2A regulatory subunit widerborst inhibits notch signaling.