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  • Search Condition : Filter (MeSH = Protein Phosphatase 2 / metabolism*)
Species Resource Title
Human and Animal Cells SH-10-TC(RCB1940) Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer.
DNA material CSII-EF-MCS-IRES2-Venus (RDB04384) , CSII-EF-MCS-IRES2-hKO1 (RDB07915) , pENTR4-H1tetOx1 (RDB07916) , CS-RfA-ETBsd (RDB07917) Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2.
Human and Animal Cells K562 TOPK is regulated by PP2A and BCR/ABL in leukemia and enhances cell proliferation.
C.elegans tm3103 , tm752 Protein phosphatase 2A is crucial for sarcomere organization in Caenorhabditis elegans striated muscle.
Human and Animal Cells MC3T3-E1(RCB1126) Regulation of NF-kB Signalling Through the PR55β-RelA Interaction in Osteoblasts.
Human and Animal Cells NIH3T3-3-4(RCB1862) Control of cell migration by the novel protein phosphatase-2A interacting protein inka2.
Human and Animal Cells MC3T3-E1(RCB1126) Inhibition of protein phosphatase 2A attenuates titanium-particle induced suppression of bone formation.
Human and Animal Cells 10T1/2(RCB0247) Reduction of protein phosphatase 2A Cα promotes in vivo bone formation and adipocyte differentiation.
Human and Animal Cells MC3T3-E1(RCB1126) , LM8(RCB1450) Protein phosphatase 2A Cα regulates proliferation, migration, and metastasis of osteosarcoma cells.
Human and Animal Cells HeLa(RCB3680) A regulatory subunit of protein phosphatase 2A, PPP2R5E, regulates the abundance of microtubule crosslinking factor 1.
Yeast BY9943 (SCU2422) Orchestrated Action of PP2A Antagonizes Atg13 Phosphorylation and Promotes Autophagy after the Inactivation of TORC1.
C.elegans tm395 , tm655 Protein phosphatase 2A-SUR-6/B55 regulates centriole duplication in C. elegans by controlling the levels of centriole assembly factors.
C.elegans tm3951 PP2A phosphatase acts upon SAS-5 to ensure centriole formation in C. elegans embryos.
Human and Animal Cells RAW 264(RCB0535) Protein phosphatase 2A Cα is involved in osteoclastogenesis by regulating RANKL and OPG expression in osteoblasts.
Human and Animal Cells Regulated interaction of protein phosphatase 1 and protein phosphatase 2A with phospholipase C-related but catalytically inactive protein.
Yeast ZDS1 , IGO2 plasmids Comparative genetic analysis of PP2A-Cdc55 regulators in budding yeast.
DNA material pLL3.7 K122 FH-TAZ-ires-GFP-TEAD-responsive-H2B mCherry (RDB13967) , pFLAG-human yes-associated protein (YAP)1 (RDB13968) , pClneoMyc-LATS1 (RDB13969) , pClneoMyc-LATS2 (RDB13970) , pClneoLuc-PP1A (RDB13971) , pClneoLuc-PP2A (RDB13972). A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.
Yeast BY4741 , BY4742 , BYP5216 Zds1/Zds2-PP2ACdc55 complex specifies signaling output from Rho1 GTPase.
Yeast BYP1613(ZDS1) Nuclear PP2A-Cdc55 prevents APC-Cdc20 activation during the spindle assembly checkpoint.
Drosophila tws02414 (DGRC#108872). The Ser/Thr phosphatase PP2A regulatory subunit widerborst inhibits notch signaling.