生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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ヒト・動物細胞
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EoL-1 cell(RCB0641)
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77152
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p53 is critical for the Aurora B kinase inhibitor-mediated apoptosis in acute myelogenous leukemia cells.
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Int J Hematol |
2010-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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PC-12(RCB0009)
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73331
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Inhibition of the RhoA/Rho kinase system attenuates catecholamine biosynthesis in PC 12 rat pheochromocytoma cells.
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Biochim Biophys Acta |
2005-10-30 |
Pubmed
Full text
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ヒト・動物細胞
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RAW 264(RCB0535)
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73191
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Piceatannol prevents lipopolysaccharide (LPS)-induced nitric oxide (NO) production and nuclear factor (NF)-kappaB activation by inhibiting IkappaB kinase (IKK).
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Microbiol Immunol |
2004-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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HeLa/Fucci(RCB2812)
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67785
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PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase.
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Sci Rep |
2015-10-27 |
Pubmed
Full text
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ヒト・動物細胞
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RERF-LC-AI(RCB0444)
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67754
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A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
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Bioorg Med Chem |
2015-5-1 |
Pubmed
Full text
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ヒト・動物細胞
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Lu99(RCB1900)
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67417
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Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
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J Med Chem |
2015-2-26 |
Pubmed
Full text
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ヒト・動物細胞
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HS-Sch-2(RCB2230)
,
YST-1(RCB2136)
,
HS-PSS(RCB2362)
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66113
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Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors.
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Mol Oncol |
2017-9-1 |
Pubmed
Full text
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ヒト・動物細胞
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293T(RCB2202)
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65722
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Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability.
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EMBO Mol Med |
2018-6-1 |
Pubmed
Full text
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ヒト・動物細胞
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C2C12(RCB0987)
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64420
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Rho-kinase as a molecular target for insulin resistance and hypertension.
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FASEB J |
2006-1-1 |
Pubmed
Full text
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シロイヌナズナ / 植物培養細胞・遺伝子
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rpc00008
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63920
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Identification of novel compounds that inhibit SnRK2 kinase activity by high-throughput screening.
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Biochem Biophys Res Commun |
2020-12-29 |
Pubmed
Full text
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ヒト・動物細胞
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OS-RC-2(RCB0735)
,
TUHR10TKB(RCB1275)
,
TUHR14TKB(RCB1383)
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63501
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Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
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Oncotarget |
2016-4-5 |
Pubmed
Full text
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ヒト・動物細胞
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NOS-10(RCB2348)
,
HuO 9N2 (O9N2)(RCB2532)
,
NOS-1(RCB1032)
,
HuO-3N1(RCB2104)
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63249
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Direct conversion of osteosarcoma to adipocytes by targeting TNIK.
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JCI Insight |
2021-2-8 |
Pubmed
Full text
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ヒト・動物細胞
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COS-7(RCB0539)
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62740
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Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
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Oncotarget |
2016-4-5 |
Pubmed
Full text
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ヒト・動物細胞
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A549(RCB0098)
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61546
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Enhancement of cisplatin-induced cytotoxicity by ROCK inhibitor through suppression of focal adhesion kinase-independent mechanism in lung carcinoma cells.
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Int J Oncol |
2003-10-1 |
Pubmed
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線虫
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tm2508
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59367
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Suppression of AMPK/aak-2 by NRF2/SKN-1 down-regulates autophagy during prolonged oxidative stress.
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FASEB J |
2019-2-1 |
Pubmed
Full text
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ショウジョウバエ
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10522R-1
,
10522R-2
,
DGRC#201488
|
54539
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Citron kinase interacts with LATS2 and inhibits its activity by occluding its hydrophobic phosphorylation motif.
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J Mol Cell Biol |
2019-12-23 |
Pubmed
Full text
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ラット
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WTC.DMY-Mrs2dmy/Kyo (strainID=19)
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47325
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Enhanced Expression of Trib3 during the Development of Myelin Breakdown in dmy Myelin Mutant Rats.
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PLoS One |
2016-12-15 |
Pubmed
Full text
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ヒト・動物細胞
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Y79(RCB1645)
,
WERI-Rb-1(RCB2146)
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44816
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Inhibition of polo-like kinase 1 promotes hyperthermia sensitivity via inactivation of heat shock transcription factor 1 in human retinoblastoma cells.
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Invest Ophthalmol Vis Sci |
2013-12-23 |
Pubmed
Full text
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ヒト・動物細胞
|
|
44220
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Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
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Oncotarget |
2012-12-1 |
Pubmed
Full text
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ヒト・動物細胞
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RERF-LC-KJ(RCB1313)
,
RERF-LC-AI(RCB0444)
,
LC-2/ad(RCB0440)
,
LC-1/sq(RCB0455)
,
LC-1F(RCB0439)
,
MS-1(RCB0725)
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43675
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Enzastaurin has anti-tumour effects in lung cancers with overexpressed JAK pathway molecules.
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Br J Cancer |
2012-2-28 |
Pubmed
Full text
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