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論文 - 一覧

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  • 検索条件 : 絞込み (MeSH = Protein Serine-Threonine Kinases / genetics*)
生物種 リソース名 タイトル
酵母 pNHK53, pMK152 Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts.
病原細菌 V. parahaemolyticus RIMD2210633 Identification of a Family of Vibrio Type III Secretion System Effectors That Contain a Conserved Serine/Threonine Kinase Domain.
ヒト・動物細胞 JHOS-2(RCB1521) , JHOS-4(RCB1678) , NIH:OVCAR-3(RCB2135) The metabolic stress-activated checkpoint LKB1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma.
ツメガエル・イモリ The dual-specificity protein kinase Clk3 is essential for Xenopus neural development.
遺伝子材料 , ヒト・動物細胞 pCDNA-FLAG-mSIK1 (RDB19160) , pCDNA-FLAG-mSIK1(S577A) (RDB19161) , pCDNA-FLAG-mSIK2 (RDB19162) , pCDNA-FLAG-mSIK2(S587A) (RDB19163) , pCDNA-FLAG-mSIK3 (RDB19164) , pCDNA-FLAG-mSIK3(S551A) (RDB19165) , 293T(RCB2202) Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.
ヒト・動物細胞 HTC/C3(RCB0452) Identification of thyroid tumor cell vulnerabilities through a siRNA-based functional screening.
線虫 tm1502 PLK-1 promotes the merger of the parental genome into a single nucleus by triggering lamina disassembly.
ヒト・動物細胞 RBE(RCB1292) , HuH-28(RCB1943) Integrin β3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma.
ヒト・動物細胞 HCT116(RCB2979) Intellectual disability-associated gain-of-function mutations in CERT1 that encodes the ceramide transport protein CERT.
ヒト・動物細胞 PC-12(RCB0009) High-level expression of the Mnb/Dyrk1A gene in brain and heart during rat early development.
ヒト・動物細胞 ATDC5(RCB0565) Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.
ショウジョウバエ 4349R-3 , 4963R-2 Elevating bioavailable iron levels in mitochondria suppresses the defective phenotypes caused by PINK1 loss-of-function in Drosophila melanogaster.
遺伝子材料 pFLAG-mRegnase-1-WT (RDB18148) , pFLAG-mRegnase-1-D141N (RDB18149) , pFLAG-mRegnase-1-KR257258AA (KRAA) (RDB18150) , pFLAG-mRoquin-1-WT (RDB18151) , pmCherry-mRegnase-1-(90-400)-D141N (RDB18152) , pmCherry-mRegnase-1-(130-400)-D141N (RDB18153) , pmRegnase-1-(130-300)-D141N-L2-mCherryX2-C1 (RDB18154) , pmRegnase-1-(3000-400)-L2-mCherryX2-C1 (RDB18155) , pTRE-mIL6CDS-mIL63'UTR (RDB18156) , pGL3-mIL6-3'UTR (RDB18157) , ... Translation-dependent unwinding of stem-loops by UPF1 licenses Regnase-1 to degrade inflammatory mRNAs.
線虫 tm4200 , tm2355 , tm2393 , tm3310 A CCRK and a MAK Kinase Modulate Cilia Branching and Length via Regulation of Axonemal Microtubule Dynamics in Caenorhabditis elegans.
ツメガエル・イモリ Involvement of Myt1 kinase in the G2 phase of the first cell cycle in Xenopus laevis.
ショウジョウバエ DGRC#115298 Scribbled Optimizes BMP Signaling through Its Receptor Internalization to the Rab5 Endosome and Promote Robust Epithelial Morphogenesis.
ショウジョウバエ Loss-of-function mutation in Hippo suppressed enlargement of lysosomes and neurodegeneration caused by dFIG4 knockdown.
ショウジョウバエ Hippo, Drosophila MST, is a novel modifier of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS.
線虫 tm1944 Genome-wide surveys reveal polarity and cytoskeletal regulators mediate LKB1-associated germline stem cell quiescence.
遺伝子材料 pKM2L-phIL1B (RDB05526) TAZ activation by Hippo pathway dysregulation induces cytokine gene expression and promotes mesothelial cell transformation.