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  • Search Condition : Filter (MeSH = Protein Tyrosine Phosphatases / metabolism*)
Species Resource Title
Drosophila DGRC#142132 , DGRC#112951 Phosphatase of Regenerating Liver-1 Selectively Times Circadian Behavior in Darkness via Function in PDF Neurons and Dephosphorylation of TIMELESS.
Human and Animal Cells GCIY(RCB0555) , Kato III(RCB2088) , MKN74(RCB1002) , NUGC-4(RCB1939) Therapeutic potential of PRL-3 targeting and clinical significance of PRL-3 genomic amplification in gastric cancer.
Human and Animal Cells RAW 264(RCB0535) , COS-7(RCB0539) A novel mitogen-activated protein kinase phosphatase is an important negative regulator of lipopolysaccharide-mediated c-Jun N-terminal kinase activation in mouse macrophage cell lines.
Silkworms A mitochondrial phosphatase PTPMT1 is essential for the early development of silkworm, Bombyx mori.
Yeast Clp1p and Mid1p form links between cell cycle progression and gene expression at cytokinesis in fission yeast.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) The Oncogenic PRL Protein Causes Acid Addiction of Cells by Stimulating Lysosomal Exocytosis.
C.elegans tm1136 , tm1811 Yeast two-hybrid screening identifies MPZ-1 and PTP-1 as candidate scaffolding proteins of metabotropic glutamate receptors in Caenorhabditis elegans.
Human and Animal Cells MC3T3-E1(RCB1126) , NIH3T3 , UE6E7-16(RCB2163) Osteopontin inhibits osteoblast responsiveness through the down-regulation of focal adhesion kinase mediated by the induction of low-molecular weight protein tyrosine phosphatase.
Drosophila The ligand Sas and its receptor PTP10D drive tumour-suppressive cell competition.
C.elegans tm1523 Wnt signalling requires MTM-6 and MTM-9 myotubularin lipid-phosphatase function in Wnt-producing cells.
C.elegans tm591 Six and Eya promote apoptosis through direct transcriptional activation of the proapoptotic BH3-only gene egl-1 in Caenorhabditis elegans.
C.elegans tm853 Regulation of Caenorhabditis elegans p53/CEP-1-dependent germ cell apoptosis by Ras/MAPK signaling.
Human and Animal Cells HuH-7(RCB1366) Glucose enhances protein tyrosine phosphatase 1B gene transcription in hepatocytes.
Human and Animal Cells RAW 264(RCB0535) Histone acetylation and activation of cAMP-response element-binding protein regulate transcriptional activation of MKP-M in lipopolysaccharide-stimulated macrophages.
Drosophila The role of Bro1- domain-containing protein Myopic in endosomal trafficking of Wnt/Wingless.
Yeast NA Functionally redundant protein phosphatase genes PTP2 and MSG5 co-regulate the calcium signaling pathway in Saccharomyces cerevisiae upon exposure to high extracellular calcium concentration.
Drosophila The Myopic-Ubpy-Hrs nexus enables endosomal recycling of Frizzled.
Yeast FY13580 Cds1 controls the release of Cdc14-like phosphatase Flp1 from the nucleolus to drive full activation of the checkpoint response to replication stress in fission yeast.
Yeast The Flp1/Clp1 phosphatase cooperates with HECT-type Pub1/2 protein-ubiquitin ligases in Schizosaccharomyces pombe.
C.elegans tm3330 , tm3733 A conserved Six-Eya cassette acts downstream of Wnt signaling to direct non-myogenic versus myogenic fates in the C. elegans postembryonic mesoderm.