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  • Search Condition : Filter (MeSH = Protein-Serine-Threonine Kinases / metabolism*)
Species Resource
DNA material WEE1Hu (RDB1204) Akt/protein kinase B-dependent phosphorylation and inactivation of WEE1Hu promote cell cycle progression at G2/M transition.
DNA material AxCANCre (RDB01748) , pCALNL5 (RDB01862). TGFbeta3-induced activation of RhoA/Rho-kinase pathway is necessary but not sufficient for epithelio-mesenchymal transdifferentiation: implications for palatogenesis.
Yeast FY13725(PY615) , FY13718(PY532) Shugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeres.
C.elegans tm597 Interactions of UNC-34 Enabled with Rac GTPases and the NIK kinase MIG-15 in Caenorhabditis elegans axon pathfinding and neuronal migration.
Yeast CD16-1 , FY9907(TP4-5A) , FY7051(JZ670) Mug27 is a meiosis-specific protein kinase that functions in fission yeast meiosis II and sporulation.
Yeast BY9004 , BY9943 The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase.
C.elegans tm1898 , tm1779 Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth.
Arabidopsis / Cultured plant cells, genes pda09214 A protein kinase family in Arabidopsis phosphorylates chloroplast precursor proteins.
Zebrafish RIKEN WT (RW) , rw021 (Tg(ath5:GFP))? , rw255(piy)? Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53.
C.elegans tm853 PLK-1 asymmetry contributes to asynchronous cell division of C. elegans embryos.
C.elegans tm1944 The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior.
C.elegans tm1997 The conserved protein SZY-20 opposes the Plk4-related kinase ZYG-1 to limit centrosome size.
C.elegans tm487 , tm1296 , tm1926 Caenorhabditis elegans WNK-STE20 pathway regulates tube formation by modulating ClC channel activity.
Mice MAK Knockout mice B6 Negative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survival.
Mice C3H/HeN-TgH(p53) Activation of interferon-stimulated genes by gamma-ray irradiation independently of the ataxia telangiectasia mutated-p53 pathway.
Yeast ? Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast.
Arabidopsis / Cultured plant cells, genes pda12751 Identification and characterization of plant Haspin kinase as a histone H3 threonine kinase.
Yeast ? Repositioning of aurora B promoted by chiasmata ensures sister chromatid mono-orientation in meiosis I.
Yeast KM311? Two histone marks establish the inner centromere and chromosome bi-orientation.
Yeast FY13784(PZ865) , FY13775(PZ405) , FY13792(PZ946) , FY13818(PX536) , FY13787(PZ901) , FY13784(PZ865) , FY13504(JX794) ? Phosphorylation of H2A by Bub1 prevents chromosomal instability through localizing shugoshin.