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  • Search Condition : Filter (MeSH = Protein-Serine-Threonine Kinases / physiology*)
Species Resource
Drosophila The Misshapen kinase regulates the size and stability of the germline ring canals in the Drosophila egg chamber.
C.elegans tm3036 A novel gene-diet pair modulates C. elegans aging.
C.elegans tm1779 , tm598 A bacterial metabolite induces glutathione-tractable proteostatic damage, proteasomal disturbances, and PINK1-dependent autophagy in C. elegans.
Drosophila JNK pathway activation is controlled by Tao/TAOK3 to modulate ethanol sensitivity.
Drosophila mtv shapes the activity gradient of the Dpp morphogen through regulation of thickveins.
C.elegans tm655 Protein phosphatase 2A cooperates with the autophagy-related kinase UNC-51 to regulate axon guidance in Caenorhabditis elegans.
C.elegans tm1944 , tm4834 , tm1714 , tm4024 S6 kinase inhibits intrinsic axon regeneration capacity via AMP kinase in Caenorhabditis elegans.
C.elegans tm4391 , tm4720 , tm4076 , tm4396 The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43.
C.elegans tm5219 A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan.
Human and Animal Cells Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals.
Human and Animal Cells O-GlcNAc modification affects the ATM-mediated DNA damage response.
Human and Animal Cells Involvement of the ATR- and ATM-dependent checkpoint responses in cell cycle arrest evoked by pierisin-1.
Human and Animal Cells A(1) adenosine receptor signal and AMPK involving caspase-9/-3 activation are responsible for adenosine-induced RCR-1 astrocytoma cell death.
Human and Animal Cells MEK kinase 1 mediates the antiapoptotic effect of the Bcr-Abl oncogene through NF-kappaB activation.
Human and Animal Cells G1-checkpoint function including a cyclin-dependent kinase 2 regulatory pathway as potential determinant of 7-hydroxystaurosporine (UCN-01)-induced apoptosis and G1-phase accumulation.
Human and Animal Cells Oncogenic and tumor suppressive roles of polo-like kinases in human hepatocellular carcinoma.
Drosophila DGRC#105935 The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway.
DNA material pEF-LRRK2-FLAG-His (RDB13973) , pEF-HERC2 (RDB13974) , pEF-NEURL4 (RDB13975) , pEGFP-C-HERC2 (RDB13976) , pEGFP-C-NEURL4 (RDB13977) , pcDNA3-NEURL4-FLAG-His (RDB13978) , pcDNA3-FLAG-HERC2 (RDB13979). The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway.
DNA material CS-RfA-EVBsd (RDB06090) , pENTR4-H1 (RDB04395) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). Polycomb-mediated loss of miR-31 activates NIK-dependent NF-κB pathway in adult T cell leukemia and other cancers.
Drosophila The Drosophila MAST kinase Drop out is required to initiate membrane compartmentalisation during cellularisation and regulates dynein-based transport.