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論文 - 一覧

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  • 検索条件 : 絞込み (MeSH = Protein-Tyrosine Kinases / antagonists & inhibitors*)
生物種 リソース名 タイトル
ヒト・動物細胞 K562 Aldo-keto reductase inhibitors increase the anticancer effects of tyrosine kinase inhibitors in chronic myelogenous leukemia.
ヒト・動物細胞 32D(RCB1145) In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor.
ヒト・動物細胞 RERF-LC-AI(RCB0444) A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
ヒト・動物細胞 Lu99(RCB1900) Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
ヒト・動物細胞 293T(RCB2202) Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability.
実験動物マウス RBRC00144 Pretransplant Short-Term Exposure of Donor Graft Cells to ITK Selective Inhibitor Ameliorates Acute Graft-versus-Host Disease by Inhibiting Effector T Cell Differentiation while Sparing Regulatory T Cells.
ヒト・動物細胞 MH7A(RCB1512) A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation.
ヒト・動物細胞 HuCCT1(RCB1960) , TFK-1(RCB2537) Inhibition of ATR Increases the Sensitivity to WEE1 Inhibitor in Biliary Tract Cancer.
ヒト・動物細胞 A549(RCB0098) Image-based compound profiling reveals a dual inhibitor of tyrosine kinase and microtubule polymerization.
ヒト・動物細胞 A549(RCB0098) Enhancement of cisplatin-induced cytotoxicity by ROCK inhibitor through suppression of focal adhesion kinase-independent mechanism in lung carcinoma cells.
ヒト・動物細胞 Ba/F3 The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models.
ヒト・動物細胞 HeLa/Fucci(RCB2812) WEE1 inhibition enhances sensitivity to hypoxia/reoxygenation in HeLa cells.
ヒト・動物細胞 StromaNKtert(RCB2350) Bruton's tyrosine kinase inhibition increases BCL-2 dependence and enhances sensitivity to venetoclax in chronic lymphocytic leukemia.
ヒト・動物細胞 K562(RCB0027) ADAM8 Is an Antigen of Tyrosine Kinase Inhibitor-Resistant Chronic Myeloid Leukemia Cells Identified by Patient-Derived Induced Pluripotent Stem Cells.
ヒト・動物細胞 HuH-7 Efficient induction of apoptosis by wee1 kinase inhibition in hepatocellular carcinoma cells.
ヒト・動物細胞 PC-9(RCB4455) Clinical outcome according to the level of preexisting epidermal growth factor receptor T790M mutation in patients with lung cancer harboring sensitive epidermal growth factor receptor mutations.
ヒト・動物細胞 KUSA-H1(RCB1990) , 9-15C(RCB2323) , TSt-4(RCB2116) Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration.
ヒト・動物細胞 Inhibition of the antigen-induced activation of rodent mast cells by putative Janus kinase 3 inhibitors WHI-P131 and WHI-P154 in a Janus kinase 3-independent manner.
ヒト・動物細胞 KU812(RCB0495) , K562 Sorafenib induces apoptosis specifically in cells expressing BCR/ABL by inhibiting its kinase activity to activate the intrinsic mitochondrial pathway.
ヒト・動物細胞 PC-9(RCB4455) Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition.