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  • Search Condition : Filter (MeSH = Proto-Oncogene Proteins / metabolism*)
Species Resource
Human and Animal Cells C2C12 Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis.
Human and Animal Cells A549 K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: possible contribution to non-invasive expansion of lung adenocarcinoma.
Human and Animal Cells RAW 264 6-(Methylsulfinyl)hexyl isothiocyanate suppresses inducible nitric oxide synthase expression through the inhibition of Janus kinase 2-mediated JNK pathway in lipopolysaccharide-activated murine macrophages.
Human and Animal Cells HeLa , Hep G2 A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis.
Human and Animal Cells RAW 264 Expression of adipose differentiation-related protein (ADRP) is conjointly regulated by PU.1 and AP-1 in macrophages.
Human and Animal Cells MKN7 , MKN45 , MKN74 COX-2 inhibitor, NS398, enhances Fas-mediated apoptosis via modulation of the PTEN-Akt pathway in human gastric carcinoma cell lines.
Human and Animal Cells RAW 264 Interleukin-15 induces IL-12 receptor beta1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling.
DNA material WEE1Hu (RDB1204) Akt/protein kinase B-dependent phosphorylation and inactivation of WEE1Hu promote cell cycle progression at G2/M transition.
Human and Animal Cells MKN28 , MKN74 Transactivation of epidermal growth factor receptor is involved in leptin-induced activation of janus-activated kinase 2 and extracellular signal-regulated kinase 1/2 in human gastric cancer cells.
DNA material pCALwL (RDB01679) Developmental alteration of nerve injury induced glial cell line-derived neurotrophic factor (GDNF) receptor expression is crucial for the determination of injured motoneuron fate.
C.elegans tm853 PLK-1 asymmetry contributes to asynchronous cell division of C. elegans embryos.
Drosophila DGRC#109634 Regulation of JNK by Src during Drosophila development.
DNA material pEFX3-FLAG-MafA (RDB07963) , pEFX3-FLAG-MafB (RDB07964) Mouse MafA, homologue of zebrafish somite Maf 1, contributes to the specific transcriptional activity through the insulin promoter.
Mice B6.129S4-Sh2b3<tm1Rmp>/Rbrc(RBRC00993) Exacerbating Pressure Overload-Induced Cardiac Hypertrophy: Novel Role of Adaptor Molecule Src Homology 2-B3.
Human and Animal Cells CIP2A modulates cell-cycle progression in human cancer cells by regulating the stability and activity of Plk1.
Human and Animal Cells By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells.
Human and Animal Cells A comprehensive search for microRNAs with expression profiles modulated by oncogenic KRAS: potential involvement of miR-31 in lung carcinogenesis.
Human and Animal Cells SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-β and bone morphogenetic protein pathways.
Human and Animal Cells SnoN/SKIL modulates proliferation through control of hsa-miR-720 transcription in esophageal cancer cells.
Human and Animal Cells Multiple-to-multiple relationships between microRNAs and target genes in gastric cancer.