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  • Search Condition : Filter (MeSH = Proto-Oncogene Proteins / physiology*)
Species Resource Title
Human and Animal Cells MRC-5 Hepatocyte growth factor upregulates E1AF that induces oral squamous cell carcinoma cell invasion by activating matrix metalloproteinase genes.
Human and Animal Cells OCUB-F(RCB0882) Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling.
Human and Animal Cells 32D(RCB1145) In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor.
Human and Animal Cells U-937 DE-4(RCB0435) Involvement of Ras/extracellular signal-regulated kinase, but not Akt pathway in risedronate-induced apoptosis of U937 cells and its suppression by cytochalasin B.
Human and Animal Cells NOS-1(RCB1032) The knock-down of overexpressed EZH2 and BMI-1 does not prevent osteosarcoma growth.
DNA material CSII-EF-MCS-IRES2-Venus (RDB04384) , pCMV-VSV-G (RDB04392) , pCAG-HIVgp (RDB04394). PU.1 acts as tumor suppressor for myeloma cells through direct transcriptional repression of IRF4.
Human and Animal Cells RAW 264(RCB0535) Bcl6 is a transcriptional repressor for the IL-18 gene.
Human and Animal Cells 32D(RCB1145) Selective apoptosis of tandemly duplicated FLT3-transformed leukemia cells by Hsp90 inhibitors.
Human and Animal Cells Regulation of the golgi structure by the alpha subunits of heterotrimeric G proteins.
Human and Animal Cells U251(RCB0461) Wnt-5a signaling is correlated with infiltrative activity in human glioma by inducing cellular migration and MMP-2.
Human and Animal Cells Oncogenic and tumor suppressive roles of polo-like kinases in human hepatocellular carcinoma.
DNA material pEFX3-FLAG-MafA (RDB07963) Characterization of the chicken L-Maf, MafB and c-Maf in crystallin gene regulation and lens differentiation.
Drosophila DGRC#109799 A protein kinase similar to MAP kinase activator acts downstream of the raf kinase in Drosophila.
Drosophila the National Institute of Genetics , the Drosophila Genetic Resource Center Kyoto for flies The Wnt5/planar cell polarity pathway regulates axonal development of the Drosophila mushroom body neuron.
Human and Animal Cells Expression of E1AF, an ets-oncogene transcription factor, highly correlates with malignant phenotype of malignant melanoma through up-regulation of the membrane-type-1 matrix metalloproteinase gene.
Drosophila Differentially expressed Drl and Drl-2 play opposing roles in Wnt5 signaling during Drosophila olfactory system development.
Cord blood stem cells for research Lipocalin 2-mediated growth suppression is evident in human erythroid and monocyte/macrophage lineage cells.
DNA material AxCANCre (RDB01748) Ribozymes targeting serine/threonine kinase Akt1 sensitize cells to anticancer drugs.
Human and Animal Cells KP4(RCB1005) Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines.
Human and Animal Cells RAW 264(RCB0535) Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1.