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論文 - 一覧

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  • 検索条件 : 絞込み (MeSH = Proto-Oncogene Proteins c-akt / antagonists & inhibitors*)
生物種 リソース名 タイトル
ヒト・動物細胞 HGC-27(RCB0500) Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer.
ヒト・動物細胞 PANC-1(RCB2095) GDP Induces PANC-1 Human Pancreatic Cancer Cell Death Preferentially under Nutrient Starvation by Inhibiting PI3K/Akt/mTOR/Autophagy Signaling Pathway.
ヒト・動物細胞 Hep G2 (-)-Epigallocatechin-3-gallate Down-regulates Doxorubicin-induced Overexpression of P-glycoprotein Through the Coordinate Inhibition of PI3K/Akt and MEK/ERK Signaling Pathways.
ヒト・動物細胞 CACO-2(RCB0988) Perifosine enhances the potential antitumor effect of 5-fluorourasil and oxaliplatin in colon cancer cells harboring the PIK3CA mutation.
ヒト・動物細胞 JHOC-5(RCB1520) Low-dose triple drug combination targeting the PI3K/AKT/mTOR pathway and the MAPK pathway is an effective approach in ovarian clear cell carcinoma.
ヒト・動物細胞 DT40(RCB1464) , ΔBLM-DT40(RCB1811) , ΔWRN-DT40(RCB1812) 3EZ,20Ac-ingenol, a catalytic inhibitor of topoisomerases, downregulates p-Akt and induces DSBs and apoptosis of DT40 cells.
ヒト・動物細胞 Akt inactivation induces endoplasmic reticulum stress-independent autophagy in fibroblasts from patients with Pompe disease.
ヒト・動物細胞 MKN28(RCB1000) Inhibition of Akt/PKB by a COX-2 inhibitor induces apoptosis in gastric cancer cells.
ヒト・動物細胞 MKN45(RCB1001) The XAF1 tumor suppressor induces autophagic cell death via upregulation of Beclin-1 and inhibition of Akt pathway.
ヒト・動物細胞 LM8(RCB1450) Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma.