Species
|
Resource
|
RRC ID
|
Title
|
Journal
|
Published
|
Link
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Human and Animal Cells
|
MC3T3-E1(RCB1126)
|
61899
|
Osteoblasts-derived TGF-beta1 enhance motility and integrin upregulation through Akt, ERK, and NF-kappaB-dependent pathway in human breast cancer cells.
|
Mol Carcinog |
2008-7-1 |
Pubmed
Full text
|
Human and Animal Cells
|
TKKK(RCB1907)
,
TGBC2TKB(RCB1130)
,
TGBC18TKB(RCB1169)
,
TGBC14TKB(RCB1186)
,
G-415(RCB2640)
,
HuCCT1(RCB1960)
|
61781
|
K-Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines.
|
Mol Oncol |
2017-9-1 |
Pubmed
Full text
|
Human and Animal Cells
|
HeLa(RCB0007)
,
Saos-2(RCB0428)
|
61244
|
Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways.
|
Development |
2011-4-1 |
Pubmed
Full text
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Human and Animal Cells
|
MC3T3-E1(RCB1126)
|
61243
|
Akt activation is required for TGF-β1-induced osteoblast differentiation of MC3T3-E1 pre-osteoblasts.
|
PLoS One |
2014-1-1 |
Pubmed
Full text
|
Human and Animal Cells
|
MCF7(RCB1904), L929
|
58712
|
GANT61 and curcumin-loaded PLGA nanoparticles for GLI1 and PI3K/Akt-mediated inhibition in breast adenocarcinoma.
|
Nanotechnology |
2020-5-1 |
Pubmed
Full text
|
Human and Animal Cells
|
MC3T3-E1(RCB1126)
|
57987
|
BMP9 directly induces rapid GSK3-β phosphorylation in a Wnt-independent manner through class I PI3K-Akt axis in osteoblasts.
|
FASEB J |
2019-11-1 |
Pubmed
Full text
|
Human and Animal Cells
|
BALL-1(RCB0256)
|
55948
|
3EZ, 20Ac-ingenol induces cell-specific apoptosis in cyclin D1 over-expression through the activation of ATR and downregulation of p-Akt.
|
Leuk Res |
2018-1-1 |
Pubmed
Full text
|
Human and Animal Cells
|
HSC-3(RCB1975)
|
54775
|
DKK3 knockdown confers negative effects on the malignant potency of head and neck squamous cell carcinoma cells via the PI3K/Akt and MAPK signaling pathways.
|
Int J Oncol |
2019-3-1 |
Pubmed
Full text
|
Human and Animal Cells
|
B16 F10(RCB2630)
|
54729
|
Pyruvic acid/ethyl pyruvate inhibits melanogenesis in B16F10 melanoma cells through PI3K/AKT, GSK3β, and ROS-ERK signaling pathways.
|
Genes Cells |
2019-1-1 |
Pubmed
Full text
|
Human and Animal Cells
|
C2C12(RCB0987)
|
54066
|
Enzymatic digest of whey protein and wheylin-1, a dipeptide released in the digest, increase insulin sensitivity in an Akt phosphorylation-dependent manner.
|
Food Funct |
2018-9-19 |
Pubmed
Full text
|
Human and Animal Cells
|
TE-1(RCB1894)
,
TE-4(RCB2097)
,
TE-5(RCB1949)
,
TE-6(RCB1950)
,
TE-8(RCB2098)
,
TE-9(RCB1988)
,
TE-10(RCB2099)
,
TE-11(RCB2100)
|
52654
|
Activation of the Dickkopf1-CKAP4 pathway is associated with poor prognosis of esophageal cancer and anti-CKAP4 antibody may be a new therapeutic drug.
|
Oncogene |
2018-6-1 |
Pubmed
Full text
|
Human and Animal Cells
|
ATDC5(RCB0565)
|
52568
|
Blocking PI3K/AKT signaling inhibits bone sclerosis in subchondral bone and attenuates post-traumatic osteoarthritis.
|
J Cell Physiol |
2018-8-1 |
Pubmed
Full text
|
Human and Animal Cells
|
CACO-2(RCB0988)
,
COLO205(RCB2127)
|
52423
|
Rebamipide suppresses 5-fluorouracil-induced cell death via the activation of Akt/mTOR pathway and regulates the expression of Bcl-2 family proteins.
|
Toxicol In Vitro |
2018-2-1 |
Pubmed
Full text
|
Human and Animal Cells
|
MG6(RCB2403)
|
51655
|
Neuronal Orphan G-Protein Coupled Receptor Proteins Mediate Plasmalogens-Induced Activation of ERK and Akt Signaling.
|
PLoS One |
2016-1-1 |
Pubmed
Full text
|
Human and Animal Cells
|
RERF-LC-AI(RCB0444)
,
IA-LM(RCB0554)
,
WA-hT(RCB2279)
|
51647
|
Claudin-18 inhibits cell proliferation and motility mediated by inhibition of phosphorylation of PDK1 and Akt in human lung adenocarcinoma A549 cells.
|
Biochim Biophys Acta |
2016-6-1 |
Pubmed
Full text
|
C.elegans
|
tm1145
,
tm7788
|
51550
|
BRAP-2 promotes DNA damage induced germline apoptosis in C. elegans through the regulation of SKN-1 and AKT-1.
|
Cell Death Differ |
2018-7-1 |
Pubmed
Full text
|
C.elegans
|
tm3335
,
tm3607
,
tm1034
,
tm399
,
tm1075
,
tm1196
|
46489
|
Reduced expression of BTBD10, an Akt activator, leads to motor neuron death.
|
Cell Death Differ |
2012-8-1 |
Pubmed
Full text
|
C.elegans
|
tm2313
,
tm399
,
tm1075
|
45813
|
Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway.
|
Nat Struct Mol Biol |
2014-12-1 |
Pubmed
Full text
|
Human and Animal Cells
|
|
45452
|
The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL.
|
Leukemia |
2015-9-1 |
Pubmed
Full text
|
Human and Animal Cells
|
|
45103
|
Receptor-type protein tyrosine phosphatase κ directly dephosphorylates CD133 and regulates downstream AKT activation.
|
Oncogene |
2015-4-9 |
Pubmed
Full text
|