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  • 検索条件 : 絞込み (MeSH = Proto-Oncogene Proteins c-met / antagonists & inhibitors)
生物種 リソース名 タイトル
ヒト・動物細胞 MKN45(RCB1001) Excessive MET signaling causes acquired resistance and addiction to MET inhibitors in the MKN45 gastric cancer cell line.
ヒト・動物細胞 A549(RCB0098) , LC-2/ad(RCB0440) Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer.
ヒト・動物細胞 PANC-1(RCB2095) MK2461, a Multitargeted Kinase Inhibitor, Suppresses the Progression of Pancreatic Cancer by Disrupting the Interaction Between Pancreatic Cancer Cells and Stellate Cells.
ヒト・動物細胞 KP4(RCB1005) ABBV-399, a c-Met Antibody-Drug Conjugate that Targets Both MET-Amplified and c-Met-Overexpressing Tumors, Irrespective of MET Pathway Dependence.
ヒト・動物細胞 HSC-4(RCB1902) , SAS(RCB1974) , Ca9-22(RCB1976) Migration of oral squamous cell carcinoma cells are induced by HGF/c-Met signalling via lamellipodia and filopodia formation.
ヒト・動物細胞 JHOC-5(RCB1520) , JHOC-7(RCB1688) , JHOC-8(RCB1723) , JHOC-9(RCB2226) Met is the most frequently amplified gene in endometriosis-associated ovarian clear cell adenocarcinoma and correlates with worsened prognosis.
ヒト・動物細胞 HuCCT1(RCB1960) , TFK-1(RCB2537) Targeting c-MET by Tivantinib through synergistic activation of JNK/c-jun pathway in cholangiocarcinoma.
ヒト・動物細胞 GCIY(RCB0555) Paracrine activation of MET promotes peritoneal carcinomatosis in scirrhous gastric cancer.
ヒト・動物細胞 GSU(RCB2278) , Kato III(RCB2088) , KE-97(RCB1435) , MKN45(RCB1001) , NUGC-4(RCB1939) A novel inhibitor of c-Met and VEGF receptor tyrosine kinases with a broad spectrum of in vivo antitumor activities.
ヒト・動物細胞 MRC-5 Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor resistance in EML4-ALK lung cancer cells.