When you enter multiple keywords separated by space, your search will contain results that match any of the keywords (OR search).
  • 20 Hits
  • Search Condition : Filter (MeSH = Proto-Oncogene Proteins c-met / antagonists & inhibitors*)
Species Resource Title
Human and Animal Cells NUGC-4(RCB1939) The novel VEGF receptor/MET-targeted kinase inhibitor TAS-115 has marked in vivo antitumor properties and a favorable tolerability profile.
Human and Animal Cells KP4(RCB1005) First-in-Man Phase I Trial of the Selective MET Inhibitor Tepotinib in Patients with Advanced Solid Tumors.
Human and Animal Cells PC-9(RCB4455) Activation of KRAS Mediates Resistance to Targeted Therapy in MET Exon 14-mutant Non-small Cell Lung Cancer.
Human and Animal Cells KP4(RCB1005) Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET.
Human and Animal Cells MKN45(RCB1001) Regulation of MET kinase inhibitor resistance by copy number of MET in gastric carcinoma cells.
Human and Animal Cells MKN45(RCB1001) In Vitro and In Vivo Activity of AMG 337, a Potent and Selective MET Kinase Inhibitor, in MET-Dependent Cancer Models.
Human and Animal Cells MKN45(RCB1001) Design, synthesis and molecular docking studies of some novel spiro[indoline-3, 4′-piperidine]-2-ones as potential c-Met inhibitors
Human and Animal Cells HS-SY-II(RCB2231) Therapeutic potential of TAS-115 via c-MET and PDGFRα signal inhibition for synovial sarcoma.
Human and Animal Cells GCIY(RCB0555) , ECC12(RCB1009) , KE-97(RCB1435) Saracatinib impairs the peritoneal dissemination of diffuse-type gastric carcinoma cells resistant to Met and fibroblast growth factor receptor inhibitors.
Human and Animal Cells MRC-5 Ability of the Met kinase inhibitor crizotinib and new generation EGFR inhibitors to overcome resistance to EGFR inhibitors.
Human and Animal Cells KP4(RCB1005) Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent.
Human and Animal Cells Indazoles as potential c-Met inhibitors: design, synthesis and molecular docking studies.
Human and Animal Cells LoVo(RCB1639) , HCT116(RCB2979) EMD 1214063 and EMD 1204831 constitute a new class of potent and highly selective c-Met inhibitors.
Human and Animal Cells A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors.
Human and Animal Cells Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks.
Human and Animal Cells Molecular predictors of sensitivity to the MET inhibitor PHA665752 in lung carcinoma cells.
Human and Animal Cells StromaNKtert(RCB2350) Targeting the pro-survival protein MET with tivantinib (ARQ 197) inhibits growth of multiple myeloma cells.
Human and Animal Cells ACC-MESO-1(RCB2292) , ACC-MESO-4(RCB2293) Inhibition of Met/HGF receptor and angiogenesis by NK4 leads to suppression of tumor growth and migration in malignant pleural mesothelioma.
Human and Animal Cells MKN45(RCB1001) Antitumor activity of SNX-2112, a synthetic heat shock protein-90 inhibitor, in MET-amplified tumor cells with or without resistance to selective MET Inhibition.
Human and Animal Cells MKN45(RCB1001) HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells.