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  • Search Condition : Filter (MeSH = Proto-Oncogene Proteins p21(ras) / genetics*)
Species Resource Title
Human and Animal Cells , DNA material PANC-1(RCB2095) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion.
Human and Animal Cells LU99(RCB1900) , LU65(RCB1967) , IA-LM(RCB0554) The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.
Human and Animal Cells PC-9(RCB4455) Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.
Human and Animal Cells MIA Paca2(RCB2094) Active macropinocytosis induction by stimulation of epidermal growth factor receptor and oncogenic Ras expression potentiates cellular uptake efficacy of exosomes.
Human and Animal Cells MRC-5 Histone Deacetylase Inhibition Enhances the Antitumor Activity of a MEK Inhibitor in Lung Cancer Cells Harboring RAS Mutations.
Human and Animal Cells MIA Paca2(RCB2094) An improved digital polymerase chain reaction protocol to capture low-copy KRAS mutations in plasma cell-free DNA by resolving 'subsampling' issues.
Human and Animal Cells PK-1(RCB1972) , PK-8(RCB2700) , PK-45P(RCB2141) , PK-59(RCB1901) , KP4(RCB1005) , NOR-P1(RCB2139) , T3M-4(RCB1021) Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.
Human and Animal Cells 293T(RCB2202) Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures.
Human and Animal Cells MIA Paca2(RCB2094) , NB1RGB(RCB0222) Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR.
Human and Animal Cells TKKK(RCB1907) , TGBC2TKB(RCB1130) , TGBC18TKB(RCB1169) , TGBC14TKB(RCB1186) , G-415(RCB2640) , HuCCT1(RCB1960) K-Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines.
Human and Animal Cells HCT116(RCB2979) , MKN45(RCB1001) Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1.
DNA material CSII-CMV-RfA (RDB04386) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations.
Human and Animal Cells T3M-4(RCB1021) Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.
Human and Animal Cells HuCCT1(RCB1960) , RBE(RCB1292) Genomic perturbations reveal distinct regulatory networks in intrahepatic cholangiocarcinoma.
Human and Animal Cells PANC-1(RCB2095) , PK-8(RCB2700) Inhibition of 15-PGDH causes Kras-driven tumor expansion through prostaglandin E2-ALDH1 signaling in the pancreas.
Mice RBRC01828 Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis.
Drosophila DGRC#109036 Regulation of cone cell formation by Canoe and Ras in the developing Drosophila eye.
Human and Animal Cells SCCKN(RCB0441) Mutational analysis of HRAS and KRAS genes in oral carcinoma cell lines.
DNA material pCMV-SP1 (RDB04267) , pGEX-SP1 (RDB05699) , pGEX-hMAZ (RDB05701) , pCMV-MAZ (RDB03219). G4-DNA formation in the HRAS promoter and rational design of decoy oligonucleotides for cancer therapy.
DNA material pGEX-hMAZ (RDB03219) , pCMV-MAZ (RDB05701). The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element.