Species
|
Resource
|
RRC ID
|
Title
|
Journal
|
Published
|
Link
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Human and Animal Cells
|
MIA Paca2(RCB2094)
,
LU65(RCB1967)
|
71616
|
Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical models.
|
Br J Cancer |
2022-3-1 |
Pubmed
Full text
|
Human and Animal Cells
,
DNA material
|
PANC-1(RCB2095)
,
CSII-CMV-MCS-IRES2-Bsd (RDB04385)
|
69647
|
Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion.
|
Elife |
2021-9-30 |
Pubmed
Full text
|
Human and Animal Cells
|
LU99(RCB1900)
,
LU65(RCB1967)
,
IA-LM(RCB0554)
|
68965
|
The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.
|
Cancer Discov |
2020-1-1 |
Pubmed
Full text
|
Human and Animal Cells
|
PC-9(RCB4455)
|
68842
|
Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.
|
Cancer Sci |
2021-9-1 |
Pubmed
Full text
|
DNA material
|
pCMV-VSV-G-RSV-Rev (RDB04393)
|
67731
|
Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction.
|
PLoS One |
2021-1-1 |
Pubmed
Full text
|
Human and Animal Cells
|
MIA Paca2(RCB2094)
,
HeLa
|
67414
|
Active macropinocytosis induction by stimulation of epidermal growth factor receptor and oncogenic Ras expression potentiates cellular uptake efficacy of exosomes.
|
Sci Rep |
2015-6-3 |
Pubmed
Full text
|
Human and Animal Cells
|
MRC-5
|
66957
|
Histone Deacetylase Inhibition Enhances the Antitumor Activity of a MEK Inhibitor in Lung Cancer Cells Harboring RAS Mutations.
|
Mol Cancer Ther |
2018-1-1 |
Pubmed
Full text
|
Human and Animal Cells
|
MIA Paca2(RCB2094)
|
65937
|
An improved digital polymerase chain reaction protocol to capture low-copy KRAS mutations in plasma cell-free DNA by resolving 'subsampling' issues.
|
Mol Oncol |
2017-10-1 |
Pubmed
Full text
|
Human and Animal Cells
|
PK-1(RCB1972)
,
PK-8(RCB2700)
,
PK-45P(RCB2141)
,
PK-59(RCB1901)
,
KP4(RCB1005)
,
NOR-P1(RCB2139)
,
T3M-4(RCB1021)
|
65156
|
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.
|
Cancer Discov |
2020-1-1 |
Pubmed
Full text
|
Human and Animal Cells
|
293T(RCB2202)
|
64157
|
Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures.
|
PLoS One |
2017-1-1 |
Pubmed
Full text
|
Human and Animal Cells
|
CACO-2(RCB0988)
|
63032
|
Low‑dose trametinib and Bcl‑xL antagonist have a specific antitumor effect in KRAS‑mutated colorectal cancer cells.
|
Int J Oncol |
2020-11-1 |
Pubmed
Full text
|
Human and Animal Cells
|
MIA Paca2(RCB2094)
,
NB1RGB(RCB0222)
|
62950
|
Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR.
|
Sci Rep |
2020-7-23 |
Pubmed
Full text
|
Human and Animal Cells
|
TKKK(RCB1907)
,
TGBC2TKB(RCB1130)
,
TGBC18TKB(RCB1169)
,
TGBC14TKB(RCB1186)
,
G-415(RCB2640)
,
HuCCT1(RCB1960)
|
61781
|
K-Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines.
|
Mol Oncol |
2017-9-1 |
Pubmed
Full text
|
Human and Animal Cells
|
HCT116(RCB2979)
,
MKN45(RCB1001)
|
59904
|
Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1.
|
Gastroenterology |
2019-2-1 |
Pubmed
Full text
|
DNA material
|
CSII-CMV-RfA (RDB04386)
,
pCMV-VSV-G-RSV-Rev (RDB04393)
,
pCAG-HIVgp (RDB04394)
|
58370
|
Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations.
|
Nat Commun |
2019-12-19 |
Pubmed
Full text
|
Human and Animal Cells
|
T3M-4(RCB1021)
|
56893
|
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.
|
Nature |
2017-6-22 |
Pubmed
Full text
|
Human and Animal Cells
|
HuCCT1(RCB1960)
,
RBE(RCB1292)
|
56611
|
Genomic perturbations reveal distinct regulatory networks in intrahepatic cholangiocarcinoma.
|
Hepatology |
2018-9-1 |
Pubmed
Full text
|
Human and Animal Cells
|
PANC-1(RCB2095)
,
PK-8(RCB2700)
|
54134
|
Inhibition of 15-PGDH causes Kras-driven tumor expansion through prostaglandin E2-ALDH1 signaling in the pancreas.
|
Oncogene |
2019-2-1 |
Pubmed
Full text
|
Mice
|
RBRC01828
|
49646
|
Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis.
|
EBioMedicine |
2018-1-1 |
Pubmed
Full text
|
Drosophila
|
DGRC#109036
|
30422
|
Regulation of cone cell formation by Canoe and Ras in the developing Drosophila eye.
|
Development |
1997-7-1 |
Pubmed
Full text
|