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  • Search Condition : Filter (MeSH = Proto-Oncogene Proteins p21(ras) / genetics*)
Species Resource Title
Human and Animal Cells MIA Paca2(RCB2094) , LU65(RCB1967) Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical models.
Human and Animal Cells , DNA material PANC-1(RCB2095) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion.
Human and Animal Cells LU99(RCB1900) , LU65(RCB1967) , IA-LM(RCB0554) The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.
Human and Animal Cells PC-9(RCB4455) Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction.
Human and Animal Cells MIA Paca2(RCB2094) , HeLa Active macropinocytosis induction by stimulation of epidermal growth factor receptor and oncogenic Ras expression potentiates cellular uptake efficacy of exosomes.
Human and Animal Cells MRC-5 Histone Deacetylase Inhibition Enhances the Antitumor Activity of a MEK Inhibitor in Lung Cancer Cells Harboring RAS Mutations.
Human and Animal Cells MIA Paca2(RCB2094) An improved digital polymerase chain reaction protocol to capture low-copy KRAS mutations in plasma cell-free DNA by resolving 'subsampling' issues.
Human and Animal Cells PK-1(RCB1972) , PK-8(RCB2700) , PK-45P(RCB2141) , PK-59(RCB1901) , KP4(RCB1005) , NOR-P1(RCB2139) , T3M-4(RCB1021) Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.
Human and Animal Cells 293T(RCB2202) Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures.
Human and Animal Cells CACO-2(RCB0988) Low‑dose trametinib and Bcl‑xL antagonist have a specific antitumor effect in KRAS‑mutated colorectal cancer cells.
Human and Animal Cells MIA Paca2(RCB2094) , NB1RGB(RCB0222) Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR.
Human and Animal Cells TKKK(RCB1907) , TGBC2TKB(RCB1130) , TGBC18TKB(RCB1169) , TGBC14TKB(RCB1186) , G-415(RCB2640) , HuCCT1(RCB1960) K-Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines.
Human and Animal Cells HCT116(RCB2979) , MKN45(RCB1001) Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1.
DNA material CSII-CMV-RfA (RDB04386) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations.
Human and Animal Cells T3M-4(RCB1021) Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.
Human and Animal Cells HuCCT1(RCB1960) , RBE(RCB1292) Genomic perturbations reveal distinct regulatory networks in intrahepatic cholangiocarcinoma.
Human and Animal Cells PANC-1(RCB2095) , PK-8(RCB2700) Inhibition of 15-PGDH causes Kras-driven tumor expansion through prostaglandin E2-ALDH1 signaling in the pancreas.
Mice RBRC01828 Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis.
Drosophila DGRC#109036 Regulation of cone cell formation by Canoe and Ras in the developing Drosophila eye.