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論文 - 一覧

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  • 検索条件 : 絞込み (MeSH = Proto-Oncogene Proteins p21(ras) / genetics*)
生物種 リソース名 タイトル
ヒト・動物細胞 MIA Paca2(RCB2094) , LU65(RCB1967) Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical models.
ヒト・動物細胞 , 遺伝子材料 PANC-1(RCB2095) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion.
ヒト・動物細胞 LU99(RCB1900) , LU65(RCB1967) , IA-LM(RCB0554) The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.
ヒト・動物細胞 PC-9(RCB4455) Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.
遺伝子材料 pCMV-VSV-G-RSV-Rev (RDB04393) Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction.
ヒト・動物細胞 MIA Paca2(RCB2094) Active macropinocytosis induction by stimulation of epidermal growth factor receptor and oncogenic Ras expression potentiates cellular uptake efficacy of exosomes.
ヒト・動物細胞 MRC-5 Histone Deacetylase Inhibition Enhances the Antitumor Activity of a MEK Inhibitor in Lung Cancer Cells Harboring RAS Mutations.
ヒト・動物細胞 MIA Paca2(RCB2094) An improved digital polymerase chain reaction protocol to capture low-copy KRAS mutations in plasma cell-free DNA by resolving 'subsampling' issues.
ヒト・動物細胞 PK-1(RCB1972) , PK-8(RCB2700) , PK-45P(RCB2141) , PK-59(RCB1901) , KP4(RCB1005) , NOR-P1(RCB2139) , T3M-4(RCB1021) Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.
ヒト・動物細胞 293T(RCB2202) Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures.
ヒト・動物細胞 CACO-2(RCB0988) Low‑dose trametinib and Bcl‑xL antagonist have a specific antitumor effect in KRAS‑mutated colorectal cancer cells.
ヒト・動物細胞 MIA Paca2(RCB2094) , NB1RGB(RCB0222) Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR.
ヒト・動物細胞 TKKK(RCB1907) , TGBC2TKB(RCB1130) , TGBC18TKB(RCB1169) , TGBC14TKB(RCB1186) , G-415(RCB2640) , HuCCT1(RCB1960) K-Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines.
ヒト・動物細胞 HCT116(RCB2979) , MKN45(RCB1001) Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1.
遺伝子材料 CSII-CMV-RfA (RDB04386) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations.
ヒト・動物細胞 T3M-4(RCB1021) Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.
ヒト・動物細胞 HuCCT1(RCB1960) , RBE(RCB1292) Genomic perturbations reveal distinct regulatory networks in intrahepatic cholangiocarcinoma.
ヒト・動物細胞 PANC-1(RCB2095) , PK-8(RCB2700) Inhibition of 15-PGDH causes Kras-driven tumor expansion through prostaglandin E2-ALDH1 signaling in the pancreas.
実験動物マウス RBRC01828 Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis.
ショウジョウバエ DGRC#109036 Regulation of cone cell formation by Canoe and Ras in the developing Drosophila eye.