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  • 9 Hits
  • Search Condition : Filter (MeSH = Purines / pharmacology*)
Species Resource Title
Human and Animal Cells KUSA-H1(RCB1990) , 9-15C(RCB2323) , UV♀2(RCB1994) , StromaNKtert(RCB2350) The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells.
Human and Animal Cells Jurkat Inhibition of JAK-STAT Signaling by Baricitinib Reduces Interferon-γ-Induced CXCL10 Production in Human Salivary Gland Ductal Cells.
Human and Animal Cells K562 Aryl Hydrocarbon Receptor Antagonist StemRegenin 1 Promotes the Expansion of Human Promyelocytic Leukemia Cell Line, NB4.
Human and Animal Cells SQ-5(RCB0110) The purine scaffold Hsp90 inhibitor PU-H71 sensitizes cancer cells to heavy ion radiation by inhibiting DNA repair by homologous recombination and non-homologous end joining.
Human and Animal Cells PC-9(RCB4455) Drug resistance originating from a TGF-β/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation.
Human and Animal Cells StromaNKtert(RCB2350) The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL.
Human and Animal Cells Evaluation and prediction of potential drug-drug interactions of linagliptin using in vitro cell culture methods.
Human and Animal Cells ST2(RCB0224) Inhibition of osteoclastogenesis by a phosphodiesterase 4 inhibitor XT-611 through synergistic action with endogenous prostaglandin E2.
Human and Animal Cells KUSA-H1(RCB1990) , 9-15C(RCB2323) , TSt-4(RCB2116) The phosphoinositide 3'-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia.