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  • 32 Hits
  • Search Condition : Filter (MeSH = Pyrazoles / pharmacology*)
Species Resource Title
Human and Animal Cells HGC-27(RCB0500) New pyrazoles incorporating pyrazolylpyrazole moiety: synthesis, anti-HCV and antitumor activity.
Human and Animal Cells PC-12(RCB0009) Dorsomorphin stimulates neurite outgrowth in PC12 cells via activation of a protein kinase A-dependent MEK-ERK1/2 signaling pathway.
Human and Animal Cells HSC-2(RCB1945) Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides.
Human and Animal Cells HSC-2(RCB1945) Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors.
Human and Animal Cells 201B7(HPS0063) A simple method of hiPSCs differentiation into insulin-producing cells is improved with vitamin C and RepSox.
Human and Animal Cells HFL-I(RCB0521) TAS-116, a Novel Hsp90 Inhibitor, Selectively Enhances Radiosensitivity of Human Cancer Cells to X-rays and Carbon Ion Radiation.
Human and Animal Cells HCT116(RCB2979) Celecoxib and 2,5-dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β-catenin signaling pathway.
Human and Animal Cells U-937 DE-4(RCB0435) Vasculo-protective effect of BMS-309403 is independent of its specific inhibition of fatty acid-binding protein 4.
Human and Animal Cells Btk^(-) DT40(RCB1468) Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia.
Human and Animal Cells Li-7(RCB1941) ASP5878, a Novel Inhibitor of FGFR1, 2, 3, and 4, Inhibits the Growth of FGF19-Expressing Hepatocellular Carcinoma.
Human and Animal Cells Ba/F3 Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor.
Human and Animal Cells BOY-12E(RCB2627) , JMSU1(RCB2227) ASP5878, a selective FGFR inhibitor, to treat FGFR3-dependent urothelial cancer with or without chemoresistance.
Human and Animal Cells Jurkat Inhibition of JAK-STAT Signaling by Baricitinib Reduces Interferon-γ-Induced CXCL10 Production in Human Salivary Gland Ductal Cells.
Human and Animal Cells MCF7(RCB1904) , A549(RCB0098) Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors.
Human and Animal Cells Ba/F3(RCB0805) Alpha-tocopherol attenuates the anti-tumor activity of crizotinib against cells transformed by NPM-ALK.
Human and Animal Cells HeLa/Fucci(RCB2812) Induction of endomitosis-like event in HeLa cells following CHK1 inhibitor treatment.
Human and Animal Cells StromaNKtert(RCB2350) Bruton's tyrosine kinase inhibition increases BCL-2 dependence and enhances sensitivity to venetoclax in chronic lymphocytic leukemia.
Human and Animal Cells PANC-1(RCB2095) Alternating magnetic field enhances cytotoxicity of Compound C.
Human and Animal Cells COS-7(RCB0539) Mizagliflozin, a novel selective SGLT1 inhibitor, exhibits potential in the amelioration of chronic constipation.
Human and Animal Cells TE-1(RCB1894) Targeted inhibition of the COP9 signalosome for treatment of cancer.