• 56 Hits
  • 検索条件 : 絞込み (MeSH = Pyrimidines / pharmacology*)
生物種 リソース名 タイトル
ヒト・動物細胞 WEHI-3(RCB0035) , Ba/F3(RCB0805) Synergistic killing effect of imatinib and simvastatin on imatinib-resistant chronic myelogenous leukemia cells.
ヒト・動物細胞 WI-38(RCB0702) Imatinib mesylate inhibits the proliferation-stimulating effect of human lung cancer-associated stromal fibroblasts on lung cancer cells.
ヒト・動物細胞 PC-12(RCB0009) Dorsomorphin stimulates neurite outgrowth in PC12 cells via activation of a protein kinase A-dependent MEK-ERK1/2 signaling pathway.
ヒト・動物細胞 WI-38(RCB0702) A liquid crystal-related compound induces cell cycle arrest at the G2/M phase and apoptosis in the A549 human non-small cell lung cancer cell line.
ヒト・動物細胞 293T(RCB2202) Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability.
ヒト・動物細胞 Btk^(-) DT40(RCB1468) Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia.
ヒト・動物細胞 JHOC-5(RCB1520) , JHOC-7(RCB1688) , JHOC-9(RCB2226) , JHOM-1(RCB1676) , JHOS-3(RCB1546) Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition.
ヒト・動物細胞 Li-7(RCB1941) ASP5878, a Novel Inhibitor of FGFR1, 2, 3, and 4, Inhibits the Growth of FGF19-Expressing Hepatocellular Carcinoma.
ヒト・動物細胞 BOY-12E(RCB2627) , JMSU1(RCB2227) ASP5878, a selective FGFR inhibitor, to treat FGFR3-dependent urothelial cancer with or without chemoresistance.
ヒト・動物細胞 PC-9(RCB4455) Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.
ヒト・動物細胞 KP4(RCB1005) Translational pharmacokinetic-pharmacodynamic modeling of preclinical and clinical data of the oral MET inhibitor tepotinib to determine the recommended phase II dose.
ヒト・動物細胞 HuCCT1(RCB1960) , TFK-1(RCB2537) Inhibition of ATR Increases the Sensitivity to WEE1 Inhibitor in Biliary Tract Cancer.
ヒト・動物細胞 A549(RCB0098) The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo.
ヒト・動物細胞 32Dcl3 Functional characterization, localization, and inhibitor sensitivity of the TPR-FGFR1 fusion in 8p11 myeloproliferative syndrome.
ヒト・動物細胞 CACO-2(RCB0988) Augmented pentose phosphate pathway plays critical roles in colorectal carcinomas.
ヒト・動物細胞 HCT116(RCB2979) , MKN45(RCB1001) Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1.
ヒト・動物細胞 RAW 264(RCB0535) Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects.
ヒト・動物細胞 409B2(HPS0076) , 610B1(HPS0331) , 10T1/2(RCB0247) Isolation of induced pluripotent stem cell-derived endothelial progenitor cells from sac-like structures.
ヒト・動物細胞 StromaNKtert(RCB2350) Bruton's tyrosine kinase inhibition increases BCL-2 dependence and enhances sensitivity to venetoclax in chronic lymphocytic leukemia.
ヒト・動物細胞 PANC-1(RCB2095) Alternating magnetic field enhances cytotoxicity of Compound C.