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  • 検索条件 : 絞込み (MeSH = Pyrimidines / therapeutic use*)
生物種 リソース名 タイトル
ヒト・動物細胞 HS-Sch-2(RCB2230) Appropriate modulation of autophagy sensitizes malignant peripheral nerve sheath tumor cells to treatment with imatinib mesylate.
ヒト・動物細胞 Ba/F3(RCB0805) Clinical Acquired Resistance to KRASG12C Inhibition through a Novel KRAS Switch-II Pocket Mutation and Polyclonal Alterations Converging on RAS-MAPK Reactivation.
ヒト・動物細胞 A549 , RERF-LC-AI(RCB0444) , RERF-LC-KJ(RCB1313) Tofacitinib overcomes an IFNγ-induced decrease in NK cell-mediated cytotoxicity via the regulation of immune-related molecules in LC-2/ad.
ヒト・動物細胞 OP9(RCB1124) Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence.
ヒト・動物細胞 DT40(RCB1464) Hypermorphic mutation of phospholipase C, γ2 acquired in ibrutinib-resistant CLL confers BTK independency upon B-cell receptor activation.
ゼブラフィッシュ Tg(cmlc2:mRFP)ko07 Identification of Potent In Vivo Autotaxin Inhibitors that Bind to Both Hydrophobic Pockets and Channels in the Catalytic Domain.
ヒト・動物細胞 KP4(RCB1005) First-in-Man Phase I Trial of the Selective MET Inhibitor Tepotinib in Patients with Advanced Solid Tumors.
ヒト・動物細胞 HGC-27(RCB0500) , GT3TKB(RCB0885) A novel carbazole topoisomerase II poison, ER-37328: potent tumoricidal activity against human solid tumors in vitro and in vivo.
ヒト・動物細胞 MCF7(RCB1904) , L929 GANT61 and curcumin-loaded PLGA nanoparticles for GLI1 and PI3K/Akt-mediated inhibition in breast adenocarcinoma.
ヒト・動物細胞 HS-SY-II(RCB2231) Therapeutic potential of TAS-115 via c-MET and PDGFRα signal inhibition for synovial sarcoma.