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Search Condition : Filter (MeSH = Pyrrolidines / chemistry*)
Species
Resource
RRC ID
Title
Journal
Published
Link
Human and Animal Cells
PC-9(RCB4455)
65037
Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.
J Med Chem
2017-4-13
Pubmed
Full text
Prokaryotes E. coli
ASKA (-) collection
,
ASKA (+) collection
59193
An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors.
Eur J Med Chem
2019-4-1
Pubmed
Full text
Mice
,
Human and Animal Cells
RBRC00806
,
Atg5^(-/-)MEF(RCB2711)
,
Atg5^(+/+)MEF(RCB2710)
54475
Novel Ridaifen-B Structure Analog Induces Apoptosis and Autophagy Depending on Pyrrolidine Side Chain.
Biol Pharm Bull
2019-1-1
Pubmed
Full text