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  • Search Condition : Filter (MeSH = RNA, Small Interfering / administration & dosage*)
Species Resource Title
Human and Animal Cells KP4(RCB1005) Nek2 siRNA therapy using a portal venous port-catheter system for liver metastasis in pancreatic cancer.
Human and Animal Cells HeLa(RCB0007) Enhanced cellular uptake and gene silencing activity of siRNA using temperature-responsive polymer-modified liposome.
Human and Animal Cells HeLa Understanding structure-activity relationships of pH-sensitive cationic lipids facilitates the rational identification of promising lipid nanoparticles for delivering siRNAs in vivo.
Human and Animal Cells OV2944-HM-1(RCB1483) Glypican-3 gene silencing for ovarian cancer using siRNA-PLGA hybrid micelles in a murine peritoneal dissemination model.
Human and Animal Cells MKN45(RCB1001) A novel intraperitoneal therapy for gastric cancer with DFP-10825, a unique RNAi therapeutic targeting thymidylate synthase, in a peritoneally disseminated xenograft model.
Human and Animal Cells Hep G2 Hepatocyte-Targeted Delivery of siRNA Polyplex with PEG-Modified Lactosylated Dendrimer/Cyclodextrin Conjugates for Transthyretin-Related Amyloidosis Therapy.
Human and Animal Cells MDA-MB-453(RCB1192) , A549 Radixin knockdown improves the accumulation and efficiency of methotrexate in tumor cells.
Human and Animal Cells MKN45(RCB1001) A simplified method for manufacturing RNAi therapeutics for local administration.
Human and Animal Cells T3M-4(RCB1021) Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.
Human and Animal Cells HeLa Neutralization of negative charges of siRNA results in improved safety and efficient gene silencing activity of lipid nanoparticles loaded with high levels of siRNA.
Human and Animal Cells NIH/3T3(RCB2767) Low Electric Treatment activates Rho GTPase via Heat Shock Protein 90 and Protein Kinase C for Intracellular Delivery of siRNA.
Human and Animal Cells Colon-26(RCB2657) In Vitro and In Vivo Tumor-Targeting siRNA Delivery Using Folate-PEG-appended Dendrimer (G4)/α-Cyclodextrin Conjugates.
Human and Animal Cells Colon-26(RCB2657) Design and evaluation of thioalkylated mannose-modified dendrimer (G3)/α-cyclodextrin conjugates as antigen-presenting cell-selective siRNA carriers.
Human and Animal Cells Colon-26(RCB2657) Preparation and evaluation of polyamidoamine dendrimer conjugate with glucuronylglucosyl-β-cyclodextrin (G3) as a novel carrier for siRNA.
Human and Animal Cells Potential use of glucuronylglucosyl-β-cyclodextrin/dendrimer conjugate (G2) as a siRNA carrier for the treatment of familial amyloidotic polyneuropathy.
Human and Animal Cells OVK18(RCB1903) Efficient siRNA delivery and tumor accumulation mediated by ionically cross-linked folic acid-poly(ethylene glycol)-chitosan oligosaccharide lactate nanoparticles: for the potential targeted ovarian cancer gene therapy.
Human and Animal Cells OS-RC-2(RCB0735) Gene silencing via RNAi and siRNA quantification in tumor tissue using MEND, a liposomal siRNA delivery system.
Human and Animal Cells HeLa(RCB0007) A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo.
Human and Animal Cells Colon-26(RCB2657) Folate-PEG-appended dendrimer conjugate with α-cyclodextrin as a novel cancer cell-selective siRNA delivery carrier.
Human and Animal Cells Potential use of lactosylated dendrimer (G3)/α-cyclodextrin conjugates as hepatocyte-specific siRNA carriers for the treatment of familial amyloidotic polyneuropathy.