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  • Search Condition : Filter (MeSH = Signal Transduction / drug effects*)
Species Resource Title
Human and Animal Cells 10T1/2(RCB0247) , PANC-1(RCB2095) New hedgehog/GLI-signaling inhibitors from Adenium obesum.
Human and Animal Cells ST2(RCB0224) Mechanisms involved in suppression of osteoclast supportive activity by transforming growth factor-β1 via the ubiquitin-proteasome system.
Human and Animal Cells PC-12(RCB0009) Oleic acid stimulates glucose uptake into adipocytes by enhancing insulin receptor signaling.
Human and Animal Cells PANC-1(RCB2095) Inhibitory activity of flavonoids from Ephedrae Herba on hypoxia signaling in PANC-1 cells and the evaluation of their mechanisms.
DNA material pENTR4-H1 (RDB04395) Regulation of alkaline ceramidase activity by the c-Src-mediated pathway.
Human and Animal Cells HuH-7 First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway.
Human and Animal Cells SK-MEL-28(RCB1930) Treatment of vemurafenib-resistant SKMEL-28 melanoma cells with paclitaxel.
Human and Animal Cells RAW 264(RCB0535) Urolithin A attenuates pro-inflammatory mediator production by suppressing PI3-K/Akt/NF-κB and JNK/AP-1 signaling pathways in lipopolysaccharide-stimulated RAW264 macrophages: Possible involvement of NADPH oxidase-derived reactive oxygen species.
Human and Animal Cells HL60(RCB0041) , U937 Statins induce apoptosis through inhibition of Ras signaling pathways and enhancement of Bim and p27 expression in human hematopoietic tumor cells.
Human and Animal Cells Hep G2 Effects of Ursodeoxycholic Acid and Insulin on Palmitate-Induced ROS Production and Down-Regulation of PI3K/Akt Signaling Activity.
Human and Animal Cells 293T(RCB2202) The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures.
Human and Animal Cells HHUA(RCB0658) Activin A inhibits growth-inhibitory signals by TGF-beta1 in differentiated human endometrial adenocarcinoma cells.
Human and Animal Cells 293(RCB1637) JNK/c-Jun signaling mediates an anti-apoptotic effect of RANKL in osteoclasts.
Human and Animal Cells A431(RCB0202) Redox cycling of 9,10-phenanthrenequinone activates epidermal growth factor receptor signaling through S-oxidation of protein tyrosine phosphatase 1B.
Human and Animal Cells A549(RCB0098) Image-based compound profiling reveals a dual inhibitor of tyrosine kinase and microtubule polymerization.
Human and Animal Cells MKN45(RCB1001) An increase in galectin-3 causes cellular unresponsiveness to IFN-γ-induced signal transduction and growth inhibition in gastric cancer cells.
Human and Animal Cells MS-5(RCB4680) Arsenic acid inhibits proliferation of skin fibroblasts, and increases cellular senescence through ROS mediated MST1-FOXO signaling pathway.
Human and Animal Cells IEC 6(RCB0993) Botulinum toxin complex increases paracellular permeability in intestinal epithelial cells via activation of p38 mitogen-activated protein kinase.
Human and Animal Cells NCC-RbC-60(RCB2213) , NCC-RbC-83(RCB2217) , NCC-RbC-54(RCB2208) Inhibition of Retinoblastoma Cell Growth by CEP1347 Through Activation of the P53 Pathway.
Human and Animal Cells 409B2(HPS0076) A Light-Inducible Hedgehog Signaling Activator Modulates Proliferation and Differentiation of Neural Cells.