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  • Search Condition : Filter (MeSH = Signal Transduction / drug effects*)
Species Resource Title
DNA material pENTR4-H1 (RDB04395) Regulation of alkaline ceramidase activity by the c-Src-mediated pathway.
Human and Animal Cells HuH-7 First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway.
Human and Animal Cells SK-MEL-28(RCB1930) Treatment of vemurafenib-resistant SKMEL-28 melanoma cells with paclitaxel.
Human and Animal Cells 293T(RCB2202) The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures.
Human and Animal Cells HHUA(RCB0658) Activin A inhibits growth-inhibitory signals by TGF-beta1 in differentiated human endometrial adenocarcinoma cells.
Human and Animal Cells 293(RCB1637) JNK/c-Jun signaling mediates an anti-apoptotic effect of RANKL in osteoclasts.
Human and Animal Cells A431(RCB0202) Redox cycling of 9,10-phenanthrenequinone activates epidermal growth factor receptor signaling through S-oxidation of protein tyrosine phosphatase 1B.
Human and Animal Cells A549(RCB0098) Image-based compound profiling reveals a dual inhibitor of tyrosine kinase and microtubule polymerization.
Human and Animal Cells MKN45(RCB1001) An increase in galectin-3 causes cellular unresponsiveness to IFN-γ-induced signal transduction and growth inhibition in gastric cancer cells.
Human and Animal Cells MS-5(RCB4680) Arsenic acid inhibits proliferation of skin fibroblasts, and increases cellular senescence through ROS mediated MST1-FOXO signaling pathway.
Human and Animal Cells IEC 6(RCB0993) Botulinum toxin complex increases paracellular permeability in intestinal epithelial cells via activation of p38 mitogen-activated protein kinase.
Human and Animal Cells 409B2(HPS0076) A Light-Inducible Hedgehog Signaling Activator Modulates Proliferation and Differentiation of Neural Cells.
Human and Animal Cells A549(RCB0098) Nintedanib inhibits epithelial-mesenchymal transition in A549 alveolar epithelial cells through regulation of the TGF-β/Smad pathway.
Human and Animal Cells HHUA(RCB0658) Metformin inhibits estrogen-dependent endometrial cancer cell growth by activating the AMPK-FOXO1 signal pathway.
Human and Animal Cells HeLa , A549 NEU3 inhibitory effect of naringin suppresses cancer cell growth by attenuation of EGFR signaling through GM3 ganglioside accumulation.
Human and Animal Cells L929(RCB2619) Platelet Supernatant Suppresses LPS-Induced Nitric Oxide Production from Macrophages Accompanied by Inhibition of NF-κB Signaling and Increased Arginase-1 Expression.
Human and Animal Cells MC3T3-E1(RCB1126) Ginsenoside Rh2(S) induces differentiation and mineralization of MC3T3-E1 cells through activation of the PKD/AMPK signaling pathways.
Human and Animal Cells TGBC2TKB(RCB1130) Targeting the hedgehog pathway for gallbladder cancer therapy?
Human and Animal Cells HL60(RCB0041) , U-937 DE-4(RCB0435) Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.
Human and Animal Cells ATDC5(RCB0565) Involvement of the phosphoinositide 3-kinase/protein kinase B signaling pathway in insulin/IGF-I-induced chondrogenesis of the mouse embryonal carcinoma-derived cell line ATDC5.